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REACTOME Pathway - PI5P Name UniProt AC Dephosphorylates following protein substrates: Dephosphorylates following non-protein substrates: PPP2CB P62714 SLC9A3R1 , CHEK1 , IKBKB , CHUK , AXIN1 , MAP3K7 , CHEK2 , MYC , CRYAA , MBP , RAF1 , TP53 , HSPB1 , ITGB1 , PRKCB , KRT8 , RB1 , CDK1 , RHO , VIM , BCL2 , MAPT , NEFH , SRC , EEF2 , H2AFX , CREB1 , PRKCA , PRKACA , RPS6KB1 , CDK2 , CAD , MAPK1 , RBL1 , AKT1 , ELF1 , SNCA , IL6ST , PRKCI , CASP3 , MAPK8 , MAP2K4 , CDKN1B , PXN , MAPKAPK2 , CSNK1E , VASP , CDK9 , RPS6KA3 , PLK1 , BCAR1 , HIST1H3A , SMAD3 , MDM2 , MAP2K1 , GAD2 , PRKCD , BAX , GOLGA2 , RBL2 , TRAF2 , STK4 , PRKAA1 , PAK1 , STK3 , ATM , PPP1R1A , CAMK2B , CAMK2G , BMPR2 , PRKG1 , CAMK1 , CDK5R1 , PRKD1 , PPP2R5A , RPS6KA1 , SMAD1 , MAPK14 , CAMK4 , PNCK , PACS1 , HDAC7 , BAD , GAD1 , SMO , CARD11 , RACGAP1 , SPHK1 , PPP1R1B , CAMK2A , AKT3 , EIF4E , RPA2 , APC , NFKBIA , RELA , RYR2 , Non-protein substrates of this phosphatase are not reported yet PPP2CA P67775 SLC9A3R1 , CHEK1 , IKBKB , CHUK , AXIN1 , MAP3K7 , CHEK2 , MYC , CRYAA , MBP , RAF1 , TP53 , HSPB1 , ITGB1 , PRKCB , KRT8 , RB1 , CDK1 , RHO , VIM , BCL2 , MAPT , NEFH , SRC , EEF2 , H2AFX , CREB1 , PRKCA , PRKACA , RPS6KB1 , CDK2 , CAD , MAPK1 , RBL1 , AKT1 , ELF1 , SNCA , IL6ST , PRKCI , CASP3 , MAPK8 , MAP2K4 , CDKN1B , PXN , MAPKAPK2 , CSNK1E , VASP , CDK9 , RPS6KA3 , PLK1 , BCAR1 , HIST1H3A , SMAD3 , MDM2 , MAP2K1 , RELA , GAD2 , PRKCD , BAX , GOLGA2 , RBL2 , TRAF2 , STK4 , PRKAA1 , PAK1 , STK3 , ATM , PPP1R1A , CAMK2B , CAMK2G , BMPR2 , PRKG1 , CAMK1 , CDK5R1 , PRKD1 , PPP2R5A , RPS6KA1 , SMAD1 , MAPK14 , CAMK4 , PNCK , PACS1 , HDAC7 , BAD , GAD1 , SMO , CARD11 , RACGAP1 , SPHK1 , PPP1R1B , CAMK2A , AKT3 , EIF4E , RPA2 , APC , NFKBIA , MAPK3 , RYR2 , SLC6A3 , PTEN , Non-protein substrates of this phosphatase are not reported yet PTPN11 Q06124 SPRY2 , SPRY1 , JAK2 , MPZL1 , EGFR , PDGFRB , SRC , SELE , IRS1 , KDR , STAT1 , STAT5A , PXN , STAT5B , SIRPA , ARHGAP5 , GAB1 , PTK2B , PAG1 , GAB2 , MAP3K4 , ERBB2 , LCK , CD28 , ERBB2 , PDCD1 , ERBB4 , Non-protein substrates of this phosphatase are not reported yet
Name UniProt AC Dephosphorylated by: EGFR P00533 CDC25A , ACP1 , PTPN1 , PTPN9 , PTPRU , PTPRJ , PTPRK , PTPRS , PTPN6 , PTPN11 , PTPN2 , DUSP3 , UBASH3B , PTPRA , PTPRB , PTPN12 , PTPRH , ESR1 P03372 DUSP22 , PTPN1 , PTPN6 , ERBB2 P04626 ACPP , PTPN9 , DUSP3 , PTPN6 , PTPN12 , PTPN11 , PTPN18 , PTPN11 , INSR P06213 PTPRF , ACP1 , PTPN1 , PTPRE , PTPN2 , DUSP3 , LCK P06239 PTPRC , PTPN22 , PTPRH , PTPN6 , PTPN11 , FYN P06241 PTPRC , PTPN18 , PTPRA , PTPRE , PTPRJ , PTPN5 , MET P08581 PTPRF , PTPN1 , PTPRB , PTPRJ , PTPN2 , PDGFRB P09619 ACP1 , PTEN , PTPN1 , PTPRJ , PTPN11 , PTPN2 , DUSP3 , KIT P10721 PTPN6 , SRC P12931 PTPN23 , ACP1 , PPP2CA , PPP2CB , PTPN1 , PTPN21 , PTPN12 , PTPRA , PTPRE , PTPRJ , PTPRH , PTPN6 , PTPN11 , PTPN2 , FGFR2 P21802 DUSP3 , MAPK3 P27361 CDC25A , DUPD1 , PTPN7 , DUSP5 , DUSP1 , DUSP4 , DUSP9 , DUSP23 , PTPRE , PTPRJ , DUSP3 , PPP2CA , PTPRR , DUSP14 , PIK3R1 P27986 PPM1A , PTPRJ , MAPK1 P28482 CDC25A , DUSP22 , DUPD1 , PTPN7 , DUSP5 , DUSP1 , DUSP4 , DUSP6 , DUSP9 , DUSP7 , DUSP2 , PPP2CA , PPP2CB , PTPRE , PTPRJ , DUSP3 , PTPRR , AKT1 P31749 ACP1 , PHLPP1 , PHLPP2 , PPP2CA , PPP2CB , PPP1CA , PPP1CB , PPP1CC , CTDSP1 , IRS1 P35568 PTPN1 , PTPN13 , PTPN11 , PPP1CA , PPP1CB , PPP1CC , PTPN11 Q06124 PTPN1 , GAB1 Q13480 PTPN1 , PTPN11 , PPP2R5A Q15172 PPP2CA , PPP2CB , ERBB4 Q15303 ACP4 , PTPN6 , PTPN11 , CD28 P10747 PTPN11 ,
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