Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
--------------------------------
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
--------------------------------
299 KEGG pathways;
876 Reactome pathways;
--------------------------------
last scientific update:
11 Mar, 2019
194 phosphatases have substrate data;
--------------------------------
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
--------------------------------
299 KEGG pathways;
876 Reactome pathways;
--------------------------------
last scientific update:
11 Mar, 2019
DEPOD - Download
Human phosphatases in DEPOD and other phosphatase-databases (Phosphatome.net and iEKPD)
Human phosphatase mappingPhosphatases (GeneName, GeneID, UniProt_AC, EC number, CATH number, Activity status)
DEPOD-2015 Family
DEPOD-2019 (CATH based superfamily, Family, Subfamily)
Phosphatome.net (SCOP Fold, SCOP fold-based superfamily, SCOP Family, SCOP Subfamily, Included in phosphatome or not)
iEKPD (Type, Group, Family)
Historic classification (Substrate specificity based Superfamily, Family, Subfamily)
Phosphataserelated Gene Ontology (GO) terms used to compile the list of human phosphatases in DEPOD
Phosphatase-related GO termsGO term
Type
Description
Human phosphatase-substrate interaction and dephosphorylation sites
Interactions between human phosphatases and their protein substrates along with the dephosphorylation sites New pairs added to DEPOD-2019Phosphatase UniProt_AC numbers
Phosphatase entry names in DEPOD
Substrate UniProt_AC numbers
Substrate entry names in DEPOD
Dephosphorylation sites
5-amino acid window around the dephosphorylation site
Bioassay type
PubMed IDs
Reliability score
Interactions between human phosphatases and their non-protein substrates along with the dephosphorylation sitesPhosphatase UniProt_AC numbers
Phosphatase entry names in DEPOD
Substrate ChEBI ID
Substrate KEGG ID
Substrate ChEBI name
Dephosphorylation sites
Bioassay type
PubMed IDs
Reliability score
Relations between protein kinases, protein phosphatases and their common substrate proteins (PSKRs)
Inter-relations between human phosphatases, kinases and their common substratesSubstrate UniProt_AC
Substrate gene names
Phosphosite and 5 amino acid window around it
Phosphorylating protein kinases (taken from PhosphoSitePlus, PhosphoELM and HPRD)
Bioassay/s (from aforementioned databases)
Literature support (from aforementioned databases)
Source database/s
Dephosphosite and 5 amino window around it
Dephosphorylating protein phosphatases
Literature support
Pathways mapped on phosphatases and their substrates
KEGG pathways and the phosphatases and their protein substrates involved therein Reactome pathways and the phosphatases and their protein substrates involved thereinPathway ID (KEGG or REACTOME)
Pathway Name
Pathway description
Dephosphorylated proteins involved in the pathway
Dephosphorylating phosphatases involved in the pathway
Mapping of DEPOD entries across different databases
Mapping across different databases