Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023

DEPOD - the human DEPhOsphorylation Database, is a manually curated database collecting human phosphatases, their experimentally verified substrates and dephosphorylation site information, and pathways in which they are involved. It also provides links to popular kinase databases and protein-protein interaction databases for these phosphatases and substrates.

Example: PTPN1 (gene name), PTP1B (protein name), P18031 (UniProt AC), 5770 (Entrez gene ID), AAH18164.1 (GenBank ID)

Browse human phosphatases Browse experimentally verified protein substrates of human phosphatases Browse experimentally verified non-protein substrates of human phosphatases Browse pathways involving human phosphatases and their substrates Browse human phosphatase-substrate network Download data in DEPOD

Please cite the following reference for this resource: Damle NP and Köhn M, "The human DEPhOsphorylation Database DEPOD: 2019 update", Database, Volume 2019, 2019, baz133, (PMID: 31836896)

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European Bioinformatics Institute European Molecular Biology Laboratory Marie Curie Actions European research council BIOSS Uni-Freiburg Uni-Freiburg Marie Curie Actions