Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name PLK1 (QuickGO)
Interactive visualization of PLK1 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 3HIH

SynonymsPLK1, PLK
Protein NamePLK1
Alternative Name(s)
Serine/threonine-protein kinase PLK1;;Polo-like kinase 1;PLK-1;Serine/threonine-protein kinase 13;STPK13;
Protein FamilyBelongs to the protein kinase superfamily Ser/Thrprotein kinase family CDC5/Polo subfamily
EntrezGene ID5347   (Comparitive Toxicogenomics)
UniProt AC (Human)P53350 (protein sequence)
Enzyme Class2.7.11.21 (BRENDA )
Molecular Weight68255 Dalton
Protein Length603 amino acids (AA)
Genome Browsers NCBI | ENSG00000166851 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG0575 | eggNOG - ENOG410XQBP
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)