Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name PPP2CA (QuickGO)
Interactive visualization PPP2CA structures
(A quick tutorial to explore the interctive visulaization)

Synonyms PPP2CA
Protein Name PPP2CA
Alternative Name(s)
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform;PP2A-alpha;;Replication protein C;RP-C;
EntrezGene ID5515   (Comparitive Toxicogenomics)
UniProt AC (Human) P67775 (protein sequence)
Enzyme ClassEC (BRENDA )
Molecular Weight35594 Dalton
Protein Length309 amino acids (AA)
Genome Browsers NCBI | ENSG00000113575 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree
Classification Superfamily: PPPL --> Family: PPP | Historic class: PSTPs --> PPP --> PP2A | CATH ID: | SCOP Fold: PPPL
Phosphatase activityactive | Catalytic signature motif: unknown
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)