Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name CAD (QuickGO)
Interactive visualization of CAD structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 4C6F

Protein NameCAD
Alternative Name(s)
CAD protein;Glutamine-dependent carbamoyl-phosphate synthase;;Aspartate carbamoyltransferase;;Dihydroorotase;
Protein FamilyIn the central section, belongs to the metallo-dependent hydrolases superfamily DHOase family CAD subfamily
EntrezGene ID790   (Comparitive Toxicogenomics)
UniProt AC (Human)P27708 (protein sequence)
Enzyme Class6.3.5.5 (BRENDA )
Molecular Weight242984 Dalton
Protein Length2225 amino acids (AA)
Genome Browsers NCBI | ENSG00000084774 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG0370 | eggNOG - COG0458 | eggNOG - COG0505 | eggNOG - COG0540
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)