Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name MAPK1 (QuickGO)
Interactive visualization of MAPK1 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 6G9H

SynonymsMAPK1, ERK2, PRKM1, PRKM2
Protein NameMAPK1
Alternative Name(s)
Mitogen-activated protein kinase 1;MAP kinase 1;MAPK 1;;ERT1;Extracellular signal-regulated kinase 2;ERK-2;MAP kinase isoform p42;p42-MAPK;Mitogen-activated protein kinase 2;MAP kinase 2;MAPK 2;
Protein FamilyBelongs to the protein kinase superfamily CMGCSer/Thr protein kinase family MAP kinase subfamily
EntrezGene ID5594   (Comparitive Toxicogenomics)
UniProt AC (Human)P28482 (protein sequence)
Enzyme Class2.7.11.24 (BRENDA )
Molecular Weight41390 Dalton
Protein Length360 amino acids (AA)
Genome Browsers NCBI | ENSG00000100030 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG0660 | eggNOG - ENOG410XNY0
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)