DEPOD - human DEPhOsphorylation Database

Name	UniProt AC	Dephosphorylates following protein substrates:	Dephosphorylates following non-protein substrates:
PPP3CB	P16298	DNM1L, CRYAA, HSPB1, JUN, MAPT, NEFH, PRKAR2A, ELK1, FLNA, CANX, CSNK1E, GSK3B, VASP, DNM2, RCAN1, DNM1, GAD2, NFATC2, PPP1R1A, SLC10A1, KSR2, SSH1, BAD, GAD1, PPP1R1B, TFEB, NFKBIA, LASP1,	Non-protein substrates of this phosphatase are not reported yet
PPP3CC	P48454	DNM1L, CRYAA, HSPB1, JUN, MAPT, NEFH, PRKAR2A, ELK1, FLNA, CANX, CSNK1E, GSK3B, VASP, DNM2, RCAN1, DNM1, GAD2, NFATC2, PPP1R1A, SLC10A1, KSR2, SSH1, BAD, GAD1, PPP1R1B, TFEB, NFKBIA, LASP1,	Non-protein substrates of this phosphatase are not reported yet
PPP3CA	Q08209	DNM1L, CRYAA, HSPB1, JUN, MAPT, NEFH, PRKAR2A, ELK1, FLNA, CANX, CSNK1E, GSK3B, VASP, DNM2, RCAN1, DNM1, GAD2, NFATC2, PPP1R1A, SLC10A1, KSR2, SSH1, BAD, GAD1, PPP1R1B, TFEB, NFKBIA, LASP1, TRPM3, ORAI1,	Non-protein substrates of this phosphatase are not reported yet

Name	UniProt AC	Dephosphorylated by:
IKBKB	O14920	PPP2CA, PPP2CB, PPM1A, PPM1B, PPM1M,
CHUK	O15111	PPP2CA, PPP2CB,
EGFR	P00533	CDC25A, ACP1, PTPN1, PTPN9, PTPRU, PTPRJ, PTPRK, PTPRS, PTPN6, PTPN11, PTPN2, DUSP3, UBASH3B, PTPRA, PTPRB, PTPN12, PTPRH,
MYC	P01106	PPP2CA, PPP2CB, CTDSP1,
RAF1	P04049	CDC25A, PPP1CA, PPP1CB, PPP1CC, PPP2CA, PPP2CB, PPP5C, PTPN1,
TP53	P04637	CDC14A, CDC14B, PPP1CA, PPP1CB, PPP1CC, PPP2CA, PPP2CB, PPM1D, DUSP26,
PRKCB	P05771	PHLPP1, PHLPP2, PPP1CA, PPP2CA, PPP2CB,
RB1	P06400	PPP1CA, PPP1CB, PPP1CC, CTDSPL, PPP2CA, PPP2CB,
CDK4	P11802	CDC25A,
SRC	P12931	PTPN23, ACP1, PPP2CA, PPP2CB, PTPN1, PTPN21, PTPN12, PTPRA, PTPRE, PTPRJ, PTPRH, PTPN6, PTPN11, PTPN2,
CREB1	P16220	PPP2CA, PPP2CB, PTEN,
PRKCA	P17252	PHLPP1, PHLPP2, PPP1CA, PPP1CB, PPP1CC, PPP2CA, PPP2CB,
PRKACA	P17612	PPP2CA, PPP2CB,
ELK1	P19419	PPP3CA, PPP3CB, PPP3CC,
RPS6KB1	P23443	PPP2CA, PPP2CB, PHLPP1, PHLPP2,
JAK1	P23458	PTPRC, PTPN2,
NFKBIA	P25963	PTPN1, PTPN13, PPP3CB, PPP3CC, PPP2CB, PPP2CA, PPP3CA,
MAPK3	P27361	CDC25A, DUPD1, PTPN7, DUSP5, DUSP1, DUSP4, DUSP9, DUSP23, PTPRE, PTPRJ, DUSP3, PPP2CA, PTPRR, DUSP14,
PIK3R1	P27986	PPM1A, PTPRJ,
MAPK1	P28482	CDC25A, DUSP22, DUPD1, PTPN7, DUSP5, DUSP1, DUSP4, DUSP6, DUSP9, DUSP7, DUSP2, PPP2CA, PPP2CB, PTPRE, PTPRJ, DUSP3, PTPRR,
AKT1	P31749	ACP1, PHLPP1, PHLPP2, PPP2CA, PPP2CB, PPP1CA, PPP1CB, PPP1CC, CTDSP1,
AKT2	P31751	PHLPP1, PHLPP2,
CTNNB1	P35222	PTPN23, PTPRF, ACP1, PTPN14, PTPN1, PTPRU, PTPRK, DUSP23,
STAT3	P40763	DUSP22, PTPN1, PTPRD, PTPRT, PTPN2,
CASP3	P42574	PPP2CA, PPP2CB,
CRK	P46108	PTPN1,
PXN	P49023	PPP2CA, PPP2CB, PTPRT, PTPN11,
GSK3B	P49841	EPM2A, PPP3CA, PPP3CB, PPP3CC, PTPN1,
MAP2K6	P52564	PPM1A,
MAPK12	P53778	PTPN3,
CASP9	P55211	PPP1CA,
BCAR1	P56945	PPP2CA, PPP2CB, PTP4A3, PTPN1, PTPN12, PTPRA, PTPRH,
GNB1	P62873	PHPT1,
CDK6	Q00534	PPM1A, PPM1B,
MDM2	Q00987	PPP2CA, PPP2CB, PPM1D,
MAP2K1	Q02750	PPP2CA, PPP2CB,
RELA	Q04206	PPP2CA, PPP4C, PPP2CB,
PTK2	Q05397	PTPN23, ACP1, PPP1CA, PPP1CB, PPP1CC, PTEN, PTPN1, PTPN12, UBASH3B,
BAX	Q07812	PPP2CA, PPP2CB,
TRAF2	Q12933	PPP2CA, PPP2CB,
NFATC2	Q13469	PPP3CA, PPP3CB, PPP3CC,
PTK2B	Q14289	PTPN12, PTPN11,
CASP8	Q14790	PTPN6,
MAPK14	Q16539	DUSP22, DUPD1, PTPN7, DUSP8, DUSP1, DUSP9, DUSP10, DUSP2, PPP2CA, PPP2CB, PPM1A, PPM1D, DUSP26, DUSP3, DUSP14,
BAK1	Q16611	PTPN5,
AKT3	Q9Y243	PHLPP1, PHLPP2, PPP2CA, PPP2CB,

ChEBI ID	KEGG ID	ChEBIasciiName	Molecule	Dephosphorylated by:
CHEBI:16595	C01245	1D-myo-inositol 1,4,5-trisphosphate		INPP5B, INPP5A, INPP5E, INPP5J, INPP5K, OCRL, SYNJ1, SYNJ2,
CHEBI:16618	C05981	1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate		TNS2, FIG4, INPP5B, INPP5E, INPP5K, OCRL, PTEN, PTPRQ, INPP5F, INPP5D, INPPL1, SYNJ1, SYNJ2, TPTE2,

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KEGG Pathway - Human cytomegalovirus infection - Homo sapiens (human)

Phosphatases regulating this pathway

Protein substrates in this pathway

Non-protein substrates in this pathway