Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name OCRL (QuickGO)
Interactive visualization OCRL structures
(A quick tutorial to explore the interctive visulaization)

Synonyms OCRL, INPP5F, OCRL1
Protein Name OCRL
Alternative Name(s)
Inositol polyphosphate 5-phosphatase OCRL-1;;Lowe oculocerebrorenal syndrome protein;
EntrezGene ID4952   (Comparitive Toxicogenomics)
UniProt AC (Human) Q01968 (protein sequence)
Enzyme ClassEC (BRENDA )
Molecular Weight104205 Dalton
Protein Length901 amino acids (AA)
Genome Browsers NCBI | ENSG00000122126 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree
Classification Superfamily: inositol-5-phosphatases (IP) | Historic class: Inositol-1,4,5-trisphosphate 5-phosphatase | CATH ID: | SCOP Fold: DNase I
Phosphatase activityactive | Catalytic signature motif: unknown
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)