Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name INPP5D (QuickGO)
Interactive visualization INPP5D structures
(A quick tutorial to explore the interctive visulaization)

Synonyms INPP5D, SHIP, SHIP1
Protein Name INPP5D
Alternative Name(s)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1;;Inositol polyphosphate-5-phosphatase of 145 kDa;SIP-145;SH2 domain-containing inositol 5'-phosphatase 1;SH2 domain-containing inositol phosphatase 1;SHIP-1;p150Ship;hp51CN;
EntrezGene ID3635   (Comparitive Toxicogenomics)
UniProt AC (Human) Q92835 (protein sequence)
Enzyme ClassEC (BRENDA )
Molecular Weight133292 Dalton
Protein Length1189 amino acids (AA)
Genome Browsers NCBI | ENSG00000168918 (Ensembl) | ENSG00000281614 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree
Classification Superfamily: inositol-5-phosphatases (IP) | Historic class: Inositol-1,4,5-trisphosphate 5-phosphatase | CATH ID: | SCOP Fold: DNase I
Phosphatase activityactive | Catalytic signature motif: unknown
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)