Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last update: 11 Mar, 2019




Gene Name DUSP6 (QuickGO)
Interactive visualization DUSP6 structures
(A quick tutorial to explore the interctive visulaization)

SynonymsDUSP6, MKP3, PYST1
Protein NameDUSP6
Alternative Name(s)
Dual specificity protein phosphatase 6;;;Dual specificity protein phosphatase PYST1;Mitogen-activated protein kinase phosphatase 3;MAP kinase phosphatase 3;MKP-3;
EntrezGene ID1848   (Comparitive Toxicogenomics)
UniProt AC (Human)Q16828 (protein sequence)
Enzyme ClassEC (BRENDA )
Molecular Weight42320 Dalton
Protein Length381 amino acids (AA)
Genome Browsers NCBI | ENSG00000139318 (Ensembl) | UCSC | 1000 Genomes
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree
Classification Superfamily: Class I Cys-based PTPs --> Family: DSP | Historic class: Class I Cys-based PTPs --> VH1-like or DSPs --> MKPs | CATH ID: | SCOP Fold: CC1
Phosphatase activityactive | Catalytic signature motif: HCLAGISR
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)