Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name MDM2 (QuickGO)
Interactive visualization of MDM2 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 4OGV

Protein NameMDM2
Alternative Name(s)
E3 ubiquitin-protein ligase Mdm2;;Double minute 2 protein;Hdm2;Oncoprotein Mdm2;RING-type E3 ubiquitin transferase Mdm2;p53-binding protein Mdm2;
Protein FamilyBelongs to the MDM2/MDM4 family
EntrezGene ID4193   (Comparitive Toxicogenomics)
UniProt AC (Human)Q00987 (protein sequence)
Enzyme Class2.3.2.27 (BRENDA )
Molecular Weight55233 Dalton
Protein Length491 amino acids (AA)
Genome Browsers NCBI | ENSG00000135679 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - ENOG410IGXG | eggNOG - ENOG41125MP
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)