Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name CHUK (QuickGO)
Interactive visualization of CHUK structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 5TQW

SynonymsCHUK, IKKA, TCF16
Protein NameCHUK
Alternative Name(s)
Inhibitor of nuclear factor kappa-B kinase subunit alpha;I-kappa-B kinase alpha;IKK-A;IKK-alpha;IkBKA;IkappaB kinase;;Conserved helix-loop-helix ubiquitous kinase;I-kappa-B kinase 1;IKK1;Nuclear factor NF-kappa-B inhibitor kinase alpha;NFKBIKA;Transcription factor 16;TCF-16;
Protein FamilyBelongs to the protein kinase superfamily Ser/Thrprotein kinase family I-kappa-B kinase subfamily
EntrezGene ID1147   (Comparitive Toxicogenomics)
UniProt AC (Human)O15111 (protein sequence)
Enzyme Class2.7.11.10 (BRENDA )
Molecular Weight84640 Dalton
Protein Length745 amino acids (AA)
Genome Browsers NCBI | ENSG00000213341 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG4250 | eggNOG - ENOG410XRMU
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)