Top
KEGG Pathway - TNF signaling pathway - Homo sapiens (human) Name UniProt AC Dephosphorylates following protein substrates: Dephosphorylates following non-protein substrates: TAB1 Q15750 Protein substrates of this phosphatase are not reported yet Non-protein substrates of this phosphatase are not reported yet PGAM5 Q96HS1 MAP3K5 , LPIN1 , DNM1L , Non-protein substrates of this phosphatase are not reported yet
Name UniProt AC Dephosphorylated by: DNM1L O00429 PPP3CA , PPP3CB , PPP3CC , PGAM5 , IKBKB O14920 PPP2CA , PPP2CB , PPM1A , PPM1B , PPM1M , CHUK O15111 PPP2CA , PPP2CB , MAP3K7 O43318 PPP2CA , PPP2CB , PPM1B , PPM1L , PPP6C , JUN P05412 PPP3CA , PPP3CB , PPP3CC , CREB1 P16220 PPP2CA , PPP2CB , PTEN , SELE P16581 PTPN11 , NFKBIA P25963 PTPN1 , PTPN13 , PPP3CB , PPP3CC , PPP2CB , PPP2CA , PPP3CA , MAPK3 P27361 CDC25A , DUPD1 , PTPN7 , DUSP5 , DUSP1 , DUSP4 , DUSP9 , DUSP23 , PTPRE , PTPRJ , DUSP3 , PPP2CA , PTPRR , DUSP14 , PIK3R1 P27986 PPM1A , PTPRJ , MAPK1 P28482 CDC25A , DUSP22 , DUPD1 , PTPN7 , DUSP5 , DUSP1 , DUSP4 , DUSP6 , DUSP9 , DUSP7 , DUSP2 , PPP2CA , PPP2CB , PTPRE , PTPRJ , DUSP3 , PTPRR , AKT1 P31749 ACP1 , PHLPP1 , PHLPP2 , PPP2CA , PPP2CB , PPP1CA , PPP1CB , PPP1CC , CTDSP1 , AKT2 P31751 PHLPP1 , PHLPP2 , CASP3 P42574 PPP2CA , PPP2CB , MAPK8 P45983 DUSP22 , DUSP8 , DUSP18 , DUSP1 , DUSP9 , DUSP10 , PPP2CA , PPP2CB , DUSP3 , MAPK9 P45984 DUSP19 , DUSP1 , DUSP4 , DUSP9 , DUSP10 , DUSP16 , DUSP3 , DUSP14 , MAP2K4 P45985 PPP2CA , PPP2CB , PPM1A , MAP2K6 P52564 PPM1A , MAPK12 P53778 PTPN3 , MAPK10 P53779 DUSP16 , MAP2K1 Q02750 PPP2CA , PPP2CB , RELA Q04206 PPP2CA , PPP4C , PPP2CB , TRAF2 Q12933 PPP2CA , PPP2CB , CASP8 Q14790 PTPN6 , MAPK14 Q16539 DUSP22 , DUPD1 , PTPN7 , DUSP8 , DUSP1 , DUSP9 , DUSP10 , DUSP2 , PPP2CA , PPP2CB , PPM1A , PPM1D , DUSP26 , DUSP3 , DUSP14 , MAP3K5 Q99683 PGAM5 , PPM1L , PPP5C , AKT3 Q9Y243 PHLPP1 , PHLPP2 , PPP2CA , PPP2CB ,
Non-protein substrates involved in this pathway are unknown (yet!)