Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name MAP2K6 (QuickGO)
Interactive visualization of MAP2K6 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 2Y8O

SynonymsMAP2K6, MEK6, MKK6, PRKMK6, SKK3
Protein NameMAP2K6
Alternative Name(s)
Dual specificity mitogen-activated protein kinase kinase 6;MAP kinase kinase 6;MAPKK 6;;MAPK/ERK kinase 6;MEK 6;Stress-activated protein kinase kinase 3;SAPK kinase 3;SAPKK-3;SAPKK3;
Protein FamilyBelongs to the protein kinase superfamily STE Ser/Thrprotein kinase family MAP kinase kinase subfamily
EntrezGene ID5608   (Comparitive Toxicogenomics)
UniProt AC (Human)P52564 (protein sequence)
Enzyme Class2.7.12.2 (BRENDA )
Molecular Weight37492 Dalton
Protein Length334 amino acids (AA)
Genome Browsers NCBI | ENSG00000108984 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG0984 | eggNOG - ENOG410XT3F
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)