Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name CASP3 (QuickGO)
Interactive visualization of CASP3 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 4JR0

SynonymsCASP3, CPP32
Protein NameCASP3
Alternative Name(s)
Caspase-3;CASP-3;;Apopain;Cysteine protease CPP32;CPP-32;Protein Yama;SREBP cleavage activity 1;SCA-1;Caspase-3 subunit p17;Caspase-3 subunit p12;
Protein FamilyBelongs to the peptidase C14A family
EntrezGene ID836   (Comparitive Toxicogenomics)
UniProt AC (Human)P42574 (protein sequence)
Enzyme Class3.4.22.56 (BRENDA )
Molecular Weight31608 Dalton
Protein Length277 amino acids (AA)
Genome Browsers NCBI | ENSG00000164305 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG3573 | eggNOG - ENOG410ZQIE
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)