Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name DUSP22 (QuickGO)
Interactive visualization DUSP22 structures
(A quick tutorial to explore the interctive visulaization)

Synonyms DUSP22, JSP1, LMWDSP2, MKPX
Protein Name DUSP22
Alternative Name(s)
Dual specificity protein phosphatase 22;;;JNK-stimulatory phosphatase-1;JSP-1;Low molecular weight dual specificity phosphatase 2;LMW-DSP2;Mitogen-activated protein kinase phosphatase x;MAP kinase phosphatase x;MKP-x;
EntrezGene ID56940   (Comparitive Toxicogenomics)
UniProt AC (Human) Q9NRW4 (protein sequence)
Enzyme ClassEC (BRENDA )
Molecular Weight20910 Dalton
Protein Length184 amino acids (AA)
Genome Browsers NCBI | ENSG00000112679 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree
Classification Superfamily: Class I Cys-based PTPs --> Family: DSP | Historic class: Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CATH ID: | SCOP Fold: CC1
Phosphatase activityactive | Catalytic signature motif: HCLAGVSR
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)