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PPM1B
Localization (UniProt annotation) Cytoplasm, cytosol Membrane Note=Weakly associates at themembrane and N-myristoylation mediates the membrane localization Function (UniProt annotation) Enzyme with a broad specificity Dephosphorylates CDK2and CDK6 in vitro Dephosphorylates PRKAA1 and PRKAA2 InhibitsTBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172' Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating andinactivating IKBKB/IKKB Catalytic Activity (UniProt annotation) [a protein]-serine/threonine phosphate + H(2)O= [a protein]-serine/threonine + phosphate Protein Sequence MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHIT
TNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNFSDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNG
QVCFSTQDHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL
ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPKVSDEAVKKDSELDKHLESRV
EEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKRNVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMR
INHRGNYRQLLEEMLTSYRLAKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGEKI
ELM Motif Motif Instance Description Motif Regex NA NA NA NA
Download FASTA sequences of PPM1B-substrates in HumansSubstrate Gene Name Substrate UniProt_AC DephosphoSite and sequence (+/-5) Bioassay Type PubMed ID View in Europe PMC Reliability of the interaction IKBKB O14920 Ser-177_ELDQGsLCTSF, Ser-181_GSLCTsFVGTL In vitro and in vivo 14585847 , 18930133 , Europe PMC ARHGDIA P52565 Ser-176_MLARGsYSIKS in vitro and in vivo 29307615 , Europe PMC MAP3K7 O43318 Ser-192_TNNKGsAAWMA In vitro 11104763 , Europe PMC CDK2 P24941 Thr-160_PVRTYtHEVVT In vitro 10934208 , Europe PMC MSN P26038 Thr-558_RDKYKtLRQIR In vitro 10480873 , Europe PMC CETN2 P41208 NA In vitro 22820751 , Europe PMC CDK9 P50750 Thr-186_QPNRYtNRVVT In vitro 18829461 , Europe PMC CDK6 Q00534 Thr-177_FQMALtSVVVT In vitro 10934208 , Europe PMC CETN1 Q12798 Thr-138_LGENLtDEELQ In vitro 22820751 , Europe PMC BAD Q92934 Thr-117 _SYPAGtEEDEG In vitro 22820751 , Europe PMC
Pathway ID Pathway Name Pathway Description (KEGG) hsa04010 MAPK signaling pathway The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals express at least four distinctly regulated groups of MAPKs, extracellular signal-related kinases (ERK)-1/2, Jun amino-terminal kinases (JNK1/2/3), p38 proteins (p38alpha/beta/gamma/delta) and ERK5, that are activated by specific MAPKKs: MEK1/2 for ERK1/2, MKK3/6 for the p38, MKK4/7 (JNKK1/2) for the JNKs, and MEK5 for ERK5. Each MAPKK, however, can be activated by more than one MAPKKK, increasing the complexity and diversity of MAPK signalling. Presumably each MAPKKK confers responsiveness to distinct stimuli. For example, activation of ERK1/2 by growth factors depends on the MAPKKK c-Raf, but other MAPKKKs may activate ERK1/2 in response to pro-inflammatory stimuli.
Pathway ID Pathway Name Pathway Description (KEGG) R-HSA-1169408 ISG15 antiviral mechanism. Interferon-stimulated gene 15 (ISG15) is a member of the ubiquitin-like (Ubl) family. It is strongly induced upon exposure to type I Interferons (IFNs), viruses, bacterial LPS, and other stresses. Once released the mature ISG15 conjugates with an array of target proteins, a process termed ISGylation. ISGylation utilizes a mechanism similar to ubiquitination, requiring a three-step enzymatic cascade. UBE1L is the ISG15 E1 activating enzyme which specifically activates ISG15 at the expense of ATP. ISG15 is then transfered from E1 to the E2 conjugating enzyme UBCH8 and then to the target protein with the aid of an ISG15 E3 ligase, such as HERC5 and EFP. Hundreds of target proteins for ISGylation have been identified. Several proteins that are part of antiviral signaling pathways, such as RIG-I, MDA5, Mx1, PKR, filamin B, STAT1, IRF3 and JAK1, have been identified as targets for ISGylation. ISG15 also conjugates some viral proteins, inhibiting viral budding and release. ISGylation appears to act either by disrupting the activity of a target protein and/or by altering its localization within the cell
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Interacting partner Detection method Interaction type PubMed IDs Interaction Score Source ABL1 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID ACTA1 Affinity Capture-MS physical 27880917 , (Europe PMC )NA BioGRID ANXA1 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct ANXA2 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct ARRB1 Affinity Capture-MS, Affinity Capture-Western, anti tag coimmunoprecipitation association, physical, physical association 17620599 , (Europe PMC )0.50 BioGRID, IntAct ARRB2 Affinity Capture-MS, Affinity Capture-Western, Co-localization, anti tag coimmunoprecipitation, proximity ligation assay association, physical, physical association 17620599 , 25241761 , (Europe PMC )0.64 BioGRID, IntAct AURKB Affinity Capture-MS physical 23443559 , (Europe PMC )NA BioGRID BPGM Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID C1orf87 Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID CASK Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID CDK1 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID CDK13 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID CDK2 Biochemical Activity, Co-purification physical 10934208 , (Europe PMC )NA BioGRID CDK6 Biochemical Activity, Co-purification physical 10934208 , (Europe PMC )NA BioGRID CERKL Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID CHUK Affinity Capture-Western, Co-localization, proximity ligation assay physical, physical association 14585847 , 25241761 , (Europe PMC )0.40 BioGRID, IntAct COQ2 Affinity Capture-MS physical 29128334 , (Europe PMC )NA BioGRID COX15 Affinity Capture-MS, cross-linking study association, physical 29128334 , (Europe PMC )0.35 BioGRID, IntAct CSNK1D Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID CSNK1E Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID CYLD Affinity Capture-MS physical 27591049 , (Europe PMC )NA BioGRID DCAF4L2 Affinity Capture-MS, Affinity Capture-Western physical 27158335 , (Europe PMC )NA BioGRID DDX53 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID ECHS1 Two-hybrid, two hybrid array physical, physical association 21988832 , (Europe PMC )0.37 BioGRID, IntAct EGFR Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID EIF4A3 Affinity Capture-MS physical 23084401 , (Europe PMC )NA BioGRID ERBB3 Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID ERBB4 Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID FBXO6 Affinity Capture-MS physical 22268729 , (Europe PMC )NA BioGRID FEZ2 Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID FNTB Affinity Capture-MS physical 26186194 , (Europe PMC )NA BioGRID GAK Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID GCH1 Affinity Capture-MS physical 19294699 , (Europe PMC )NA BioGRID GSN Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct HEATR5A Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID HERC2 Affinity Capture-MS physical 25476789 , (Europe PMC )NA BioGRID HIP1R Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID HIST1H2AE Affinity Capture-MS physical 27880917 , (Europe PMC )NA BioGRID HIST1H3E Affinity Capture-MS physical 26527279 , (Europe PMC )NA BioGRID HSPA2 Affinity Capture-MS physical 27880917 , (Europe PMC )NA BioGRID IKBKB Affinity Capture-Western, Biochemical Activity physical 14585847 , (Europe PMC )NA BioGRID IKBKG Affinity Capture-Western physical 14585847 , (Europe PMC )NA BioGRID ISG15 Affinity Capture-MS, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation covalent binding, physical 16872604 , 16884686 , (Europe PMC )0.56 BioGRID, IntAct, MINT KARS Proximity Label-MS physical 27880917 , (Europe PMC )NA BioGRID KDR Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID KIF15 Proximity Label-MS physical 27880917 , (Europe PMC )NA BioGRID KRT18 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct LRRK1 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID MAGOH Affinity Capture-MS physical 23084401 , (Europe PMC )NA BioGRID MAP3K7 Affinity Capture-Western, Reconstituted Complex physical 11104763 , (Europe PMC )NA BioGRID MAP4K5 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID MAPK8 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID MINDY2 Affinity Capture-MS physical 26186194 , 28514442 , (Europe PMC )NA BioGRID NAA10 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID NOS2 Affinity Capture-MS physical 23438482 , (Europe PMC )NA BioGRID NR1I3 Affinity Capture-MS physical 26186194 , 28514442 , (Europe PMC )NA BioGRID PABPC4 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct PAK4 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID PAN2 Affinity Capture-MS physical 23398456 , (Europe PMC )NA BioGRID PARK7 Affinity Capture-MS physical 29128334 , (Europe PMC )NA BioGRID PAXX Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID PKN2 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID PPARG Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity physical 23320500 , (Europe PMC )NA BioGRID PPM1A Affinity Capture-MS physical 26186194 , 28514442 , (Europe PMC )NA BioGRID PPP2CA Co-purification physical 10934208 , (Europe PMC )NA BioGRID PRKCI Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID PTK7 Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID PVR Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID RASGRP1 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct ROR1 Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID ROR2 Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID RYK Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID S100A8 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct SKI Affinity Capture-MS physical 25670202 , (Europe PMC )NA BioGRID SOAT1 Affinity Capture-MS, cross-linking study association, physical 29128334 , (Europe PMC )0.35 BioGRID, IntAct SOD1 Affinity Capture-MS, cross-linking study association, physical 29128334 , (Europe PMC )0.35 BioGRID, IntAct SPTAN1 Affinity Capture-MS physical 27880917 , (Europe PMC )NA BioGRID SPTBN1 Affinity Capture-MS physical 27880917 , (Europe PMC )NA BioGRID STK40 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID THUMPD3 Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID TLE4 Affinity Capture-MS, Affinity Capture-Western physical 22169276 , (Europe PMC )NA BioGRID UBL7 Co-fractionation physical 22939629 , (Europe PMC )NA BioGRID VAV2 Two-hybrid, two hybrid physical, physical association 18654987 , (Europe PMC )0.37 BioGRID, IntAct VCP Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , 23443559 , (Europe PMC )0.40 BioGRID, IntAct VDAC1 Affinity Capture-MS, cross-linking study association, physical 29128334 , (Europe PMC )0.35 BioGRID, IntAct VHL Affinity Capture-MS physical 21942715 , (Europe PMC )NA BioGRID VIL1 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct VIM Affinity Capture-MS physical 27880917 , (Europe PMC )NA BioGRID XPO1 Affinity Capture-MS physical 26673895 , (Europe PMC )NA BioGRID YWHAE Affinity Capture-MS, Affinity Capture-Western physical 20462248 , (Europe PMC )NA BioGRID
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Interacting partner Detection method Interaction type PubMed IDs Interaction Score Source ANXA2 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct ARRB1 Affinity Capture-MS, Affinity Capture-Western, anti tag coimmunoprecipitation association, physical, physical association 17620599 , (Europe PMC )0.50 BioGRID, IntAct ARRB2 Affinity Capture-MS, Affinity Capture-Western, Co-localization, anti tag coimmunoprecipitation, proximity ligation assay association, physical, physical association 17620599 , 25241761 , (Europe PMC )0.64 BioGRID, IntAct CHUK Affinity Capture-Western, Co-localization, proximity ligation assay physical, physical association 14585847 , 25241761 , (Europe PMC )0.40 BioGRID, IntAct COQ2 cross-linking study association 29128334 , (Europe PMC )0.35 IntAct COX15 Affinity Capture-MS, cross-linking study association, physical 29128334 , (Europe PMC )0.35 BioGRID, IntAct ECHS1 Two-hybrid, two hybrid array physical, physical association 21988832 , (Europe PMC )0.37 BioGRID, IntAct FOS display technology physical association 20195357 , (Europe PMC )0.40 IntAct GRB2 anti tag coimmunoprecipitation association 21706016 , (Europe PMC )0.35 IntAct GSN Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct IFT88 anti tag coimmunoprecipitation association 27173435 , (Europe PMC )0.35 IntAct ISG15 Affinity Capture-MS, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation covalent binding, physical 16872604 , 16884686 , (Europe PMC )0.56 BioGRID, IntAct, MINT KRT18 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct MAGEA6 anti bait coimmunoprecipitation physical association 17353931 , (Europe PMC )0.40 IntAct MARK3 phosphatase assay physical association 12556533 , (Europe PMC )0.40 IntAct, MINT PABPC4 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct PARK7 cross-linking study association 29128334 , (Europe PMC )0.35 IntAct RASGRP1 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct S100A8 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct SOAT1 Affinity Capture-MS, cross-linking study association, physical 29128334 , (Europe PMC )0.35 BioGRID, IntAct SOD1 Affinity Capture-MS, cross-linking study association, physical 29128334 , (Europe PMC )0.35 BioGRID, IntAct VAV2 Two-hybrid, two hybrid physical, physical association 18654987 , (Europe PMC )0.37 BioGRID, IntAct VCP Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , 23443559 , (Europe PMC )0.40 BioGRID, IntAct VDAC1 Affinity Capture-MS, cross-linking study association, physical 29128334 , (Europe PMC )0.35 BioGRID, IntAct VIL1 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct
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Interacting partner Detection method Interaction type PubMed IDs Interaction Score Source ABL1 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID ACTA1 Affinity Capture-MS physical 27880917 , (Europe PMC )NA BioGRID ANXA1 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct ANXA2 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct ARRB1 Affinity Capture-MS, Affinity Capture-Western, anti tag coimmunoprecipitation association, physical, physical association 17620599 , (Europe PMC )0.50 BioGRID, IntAct ARRB2 Affinity Capture-MS, Affinity Capture-Western, Co-localization, anti tag coimmunoprecipitation, proximity ligation assay association, physical, physical association 17620599 , 25241761 , (Europe PMC )0.64 BioGRID, IntAct AURKB Affinity Capture-MS physical 23443559 , (Europe PMC )NA BioGRID BPGM Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID C1orf87 Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID CASK Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID CDK1 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID CDK13 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID CDK2 Biochemical Activity, Co-purification physical 10934208 , (Europe PMC )NA BioGRID CDK6 Biochemical Activity, Co-purification physical 10934208 , (Europe PMC )NA BioGRID CERKL Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID CHUK Affinity Capture-Western, Co-localization, proximity ligation assay physical, physical association 14585847 , 25241761 , (Europe PMC )0.40 BioGRID, IntAct COQ2 Affinity Capture-MS physical 29128334 , (Europe PMC )NA BioGRID COQ2 cross-linking study association 29128334 , (Europe PMC )0.35 IntAct COX15 Affinity Capture-MS, cross-linking study association, physical 29128334 , (Europe PMC )0.35 BioGRID, IntAct CSNK1D Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID CSNK1E Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID CYLD Affinity Capture-MS physical 27591049 , (Europe PMC )NA BioGRID DCAF4L2 Affinity Capture-MS, Affinity Capture-Western physical 27158335 , (Europe PMC )NA BioGRID DDX53 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID ECHS1 Two-hybrid, two hybrid array physical, physical association 21988832 , (Europe PMC )0.37 BioGRID, IntAct EGFR Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID EIF4A3 Affinity Capture-MS physical 23084401 , (Europe PMC )NA BioGRID ERBB3 Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID ERBB4 Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID FBXO6 Affinity Capture-MS physical 22268729 , (Europe PMC )NA BioGRID FEZ2 Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID FNTB Affinity Capture-MS physical 26186194 , (Europe PMC )NA BioGRID FOS display technology physical association 20195357 , (Europe PMC )0.40 IntAct GAK Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID GCH1 Affinity Capture-MS physical 19294699 , (Europe PMC )NA BioGRID GRB2 anti tag coimmunoprecipitation association 21706016 , (Europe PMC )0.35 IntAct GSN Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct HEATR5A Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID HERC2 Affinity Capture-MS physical 25476789 , (Europe PMC )NA BioGRID HIP1R Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID HIST1H2AE Affinity Capture-MS physical 27880917 , (Europe PMC )NA BioGRID HIST1H3E Affinity Capture-MS physical 26527279 , (Europe PMC )NA BioGRID HSPA2 Affinity Capture-MS physical 27880917 , (Europe PMC )NA BioGRID IFT88 anti tag coimmunoprecipitation association 27173435 , (Europe PMC )0.35 IntAct IKBKB Affinity Capture-Western, Biochemical Activity physical 14585847 , (Europe PMC )NA BioGRID IKBKG Affinity Capture-Western physical 14585847 , (Europe PMC )NA BioGRID ISG15 Affinity Capture-MS, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation covalent binding, physical 16872604 , 16884686 , (Europe PMC )0.56 BioGRID, IntAct, MINT KARS Proximity Label-MS physical 27880917 , (Europe PMC )NA BioGRID KDR Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID KIF15 Proximity Label-MS physical 27880917 , (Europe PMC )NA BioGRID KRT18 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct LRRK1 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID MAGEA6 anti bait coimmunoprecipitation physical association 17353931 , (Europe PMC )0.40 IntAct MAGOH Affinity Capture-MS physical 23084401 , (Europe PMC )NA BioGRID MAP3K7 Affinity Capture-Western, Reconstituted Complex physical 11104763 , (Europe PMC )NA BioGRID MAP4K5 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID MAPK8 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID MARK3 phosphatase assay physical association 12556533 , (Europe PMC )0.40 IntAct, MINT MINDY2 Affinity Capture-MS physical 26186194 , 28514442 , (Europe PMC )NA BioGRID NAA10 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID NOS2 Affinity Capture-MS physical 23438482 , (Europe PMC )NA BioGRID NR1I3 Affinity Capture-MS physical 26186194 , 28514442 , (Europe PMC )NA BioGRID PABPC4 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct PAK4 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID PAN2 Affinity Capture-MS physical 23398456 , (Europe PMC )NA BioGRID PARK7 Affinity Capture-MS physical 29128334 , (Europe PMC )NA BioGRID PARK7 cross-linking study association 29128334 , (Europe PMC )0.35 IntAct PAXX Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID PKN2 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID PPARG Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity physical 23320500 , (Europe PMC )NA BioGRID PPM1A Affinity Capture-MS physical 26186194 , 28514442 , (Europe PMC )NA BioGRID PPP2CA Co-purification physical 10934208 , (Europe PMC )NA BioGRID PRKCI Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID PTK7 Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID PVR Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID RASGRP1 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct ROR1 Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID ROR2 Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID RYK Two-hybrid physical 28065597 , (Europe PMC )NA BioGRID S100A8 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct SKI Affinity Capture-MS physical 25670202 , (Europe PMC )NA BioGRID SOAT1 Affinity Capture-MS, cross-linking study association, physical 29128334 , (Europe PMC )0.35 BioGRID, IntAct SOD1 Affinity Capture-MS, cross-linking study association, physical 29128334 , (Europe PMC )0.35 BioGRID, IntAct SPTAN1 Affinity Capture-MS physical 27880917 , (Europe PMC )NA BioGRID SPTBN1 Affinity Capture-MS physical 27880917 , (Europe PMC )NA BioGRID STK40 Co-fractionation physical 26344197 , (Europe PMC )NA BioGRID THUMPD3 Affinity Capture-MS physical 28514442 , (Europe PMC )NA BioGRID TLE4 Affinity Capture-MS, Affinity Capture-Western physical 22169276 , (Europe PMC )NA BioGRID UBL7 Co-fractionation physical 22939629 , (Europe PMC )NA BioGRID VAV2 Two-hybrid, two hybrid physical, physical association 18654987 , (Europe PMC )0.37 BioGRID, IntAct VCP Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , 23443559 , (Europe PMC )0.40 BioGRID, IntAct VDAC1 Affinity Capture-MS, cross-linking study association, physical 29128334 , (Europe PMC )0.35 BioGRID, IntAct VHL Affinity Capture-MS physical 21942715 , (Europe PMC )NA BioGRID VIL1 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 , (Europe PMC )0.40 BioGRID, IntAct VIM Affinity Capture-MS physical 27880917 , (Europe PMC )NA BioGRID XPO1 Affinity Capture-MS physical 26673895 , (Europe PMC )NA BioGRID YWHAE Affinity Capture-MS, Affinity Capture-Western physical 20462248 , (Europe PMC )NA BioGRID