Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name CDC25A (QuickGO)
Interactive visualization CDC25A structures
(A quick tutorial to explore the interctive visulaization)

Synonyms CDC25A
Protein Name CDC25A
Alternative Name(s)
M-phase inducer phosphatase 1;;Dual specificity phosphatase Cdc25A;
EntrezGene ID993   (Comparitive Toxicogenomics)
UniProt AC (Human) P30304 (protein sequence)
Enzyme ClassEC (BRENDA )
Molecular Weight59087 Dalton
Protein Length524 amino acids (AA)
Genome Browsers NCBI | ENSG00000164045 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree
Classification Superfamily: Class III Cys-based PTPs --> Family: CDC25 | Historic class: Class III Cys-based PTPs --> CDC25s | CATH ID: | SCOP Fold: CC3
Phosphatase activityactive | Catalytic signature motif: HCEFSSER
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)