Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name PIK3R1 (QuickGO)
Interactive visualization of PIK3R1 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 1PIC

SynonymsPIK3R1, GRB1
Protein NamePIK3R1
Alternative Name(s)
Phosphatidylinositol 3-kinase regulatory subunit alpha;PI3-kinase regulatory subunit alpha;PI3K regulatory subunit alpha;PtdIns-3-kinase regulatory subunit alpha;Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha;PI3-kinase subunit p85-alpha;PtdIns-3-kinase regulatory subunit p85-alpha;
Protein FamilyBelongs to the PI3K p85 subunit family
EntrezGene ID5295   (Comparitive Toxicogenomics)
UniProt AC (Human)P27986 (protein sequence)
Enzyme ClassN/A
Molecular Weight83598 Dalton
Protein Length724 amino acids (AA)
Genome Browsers NCBI | ENSG00000145675 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG4637 | eggNOG - ENOG410XP6R
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)