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KEGG Pathway - cAMP signaling pathway - Homo sapiens (human) Name UniProt AC Dephosphorylates following protein substrates: Dephosphorylates following non-protein substrates: PPP1CC P36873 FXYD1 , AURKA , AXIN1 , AHCYL1 , NCOR1 , SRSF10 , MBP , RAF1 , TP53 , EIF2S1 , RB1 , MAPT , H2AFX , PRKCA , TNNI3 , RYR1 , CAD , NOS3 , CDC25C , AKT1 , PTPN7 , IRS1 , TGFBR1 , CASP2 , TNNT2 , CSNK1E , HIST1H3A , CENPE , GAD2 , PTK2 , PRKCD , STK4 , STK3 , ATM , IKZF1 , CAMK2G , POLD3 , PRKD1 , BAD , MASTL , GAD1 , SMO , CEP250 , CAMK2A , SF3B1 , POLR2A , TTK , RYR2 , Non-protein substrates of this phosphatase are not reported yet PPP1CA P62136 AURKA , AXIN1 , AHCYL1 , TBC1D4 , NCOR1 , SRSF10 , MBP , RAF1 , TP53 , EIF2S1 , PRKCB , RB1 , MAPT , H2AFX , PRKCA , TNNI3 , EIF2AK2 , LMNB1 , RYR1 , CAD , NOS3 , CDC25C , AKT1 , PTPN7 , IRS1 , TGFBR1 , BRCA1 , CASP2 , TNNT2 , CSNK1E , CDK9 , CASP9 , PPP1CA , GAD2 , PTK2 , PRKCD , STK4 , STK3 , IKZF1 , CAMK2G , POLD3 , PRKD1 , PARD3 , BAD , MASTL , GAD1 , SMO , CEP250 , CAMK2A , SF3B1 , SF3B1 , POLR2A , RYR2 , SRSF1 , SLC6A3 , SENP3 , Non-protein substrates of this phosphatase are not reported yet PPP1CB P62140 AURKA , AXIN1 , AHCYL1 , NCOR1 , SRSF10 , MBP , RAF1 , TP53 , EIF2S1 , RB1 , MAPT , H2AFX , PRKCA , TNNI3 , RYR1 , CAD , NOS3 , CDC25C , AKT1 , PTPN7 , IRS1 , TGFBR1 , CASP2 , TNNT2 , CSNK1E , GAD2 , PTK2 , PRKCD , STK4 , STK3 , IKZF1 , CAMK2G , POLD3 , PRKD1 , BAD , MASTL , GAD1 , SMO , CEP250 , CAMK2A , SF3B1 , POLR2A , RYR2 , CDC5L , Non-protein substrates of this phosphatase are not reported yet
Name UniProt AC Dephosphorylated by: FXYD1 O00168 PPP1CC , RAF1 P04049 CDC25A , PPP1CA , PPP1CB , PPP1CC , PPP2CA , PPP2CB , PPP5C , PTPN1 , JUN P05412 PPP3CA , PPP3CB , PPP3CC , CREB1 P16220 PPP2CA , PPP2CB , PTEN , PRKACA P17612 PPP2CA , PPP2CB , TNNI3 P19429 PPP1CA , PPP1CB , PPP1CC , NFKBIA P25963 PTPN1 , PTPN13 , PPP3CB , PPP3CC , PPP2CB , PPP2CA , PPP3CA , MAPK3 P27361 CDC25A , DUPD1 , PTPN7 , DUSP5 , DUSP1 , DUSP4 , DUSP9 , DUSP23 , PTPRE , PTPRJ , DUSP3 , PPP2CA , PTPRR , DUSP14 , PIK3R1 P27986 PPM1A , PTPRJ , MAPK1 P28482 CDC25A , DUSP22 , DUPD1 , PTPN7 , DUSP5 , DUSP1 , DUSP4 , DUSP6 , DUSP9 , DUSP7 , DUSP2 , PPP2CA , PPP2CB , PTPRE , PTPRJ , DUSP3 , PTPRR , AKT1 P31749 ACP1 , PHLPP1 , PHLPP2 , PPP2CA , PPP2CB , PPP1CA , PPP1CB , PPP1CC , CTDSP1 , AKT2 P31751 PHLPP1 , PHLPP2 , MAPK8 P45983 DUSP22 , DUSP8 , DUSP18 , DUSP1 , DUSP9 , DUSP10 , PPP2CA , PPP2CB , DUSP3 , MAPK9 P45984 DUSP19 , DUSP1 , DUSP4 , DUSP9 , DUSP10 , DUSP16 , DUSP3 , DUSP14 , MAPK10 P53779 DUSP16 , PPP1CA P62136 PPP1CA , MAP2K1 Q02750 PPP2CA , PPP2CB , RELA Q04206 PPP2CA , PPP4C , PPP2CB , PAK1 Q13153 PPM1F , PPM1E , PPP2CA , PPP2CB , PPM1A , CAMK2B Q13554 PPP2CA , PPP2CB , CAMK2G Q13555 PPP1CA , PPP1CB , PPP1CC , PPP2CA , PPP2CB , CTDSPL , CAMK4 Q16566 PPM1F , PPM1E , PPP2CA , PPP2CB , BAD Q92934 ALPL , PPP1CA , PPP1CB , PPP1CC , PPP2CA , PPP2CB , PPP3CA , PPP3CB , PPP3CC , PPM1B , PPP5C , PPP1R1B Q9UD71 PPP2CA , PPP2CB , PPP3CA , PPP3CB , PPP3CC , CAMK2A Q9UQM7 PPM1F , PPP1CA , PPP1CB , PPP1CC , PPP2CA , PPP2CB , AKT3 Q9Y243 PHLPP1 , PHLPP2 , PPP2CA , PPP2CB , RYR2 Q92736 PPP1CC , PPP1CA , PPP1CB , PPP2CB , PPP2CA , ORAI1 Q96D31 PPP3CA ,
ChEBI ID KEGG ID ChEBIasciiName Molecule Dephosphorylated by: CHEBI:16027 C00020 adenosine 5'-monophosphate ACPP , ALPL , NT5E , NT5C1A , CHEBI:16337 C00416 phosphatidic acid ACPP , PLPP5 , PLPP4 , LPIN1 , LPIN2 , LPIN3 , PLPPR2 , PLPPR3 , PLPPR4 , PLPP1 , PLPP3 , PLPP2 , PLPP6 , CHEBI:16595 C01245 1D-myo-inositol 1,4,5-trisphosphate INPP5B , INPP5A , INPP5E , INPP5J , INPP5K , OCRL , SYNJ1 , SYNJ2 ,
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