Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name CASP2 (QuickGO)
Interactive visualization of CASP2 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 2P2C

SynonymsCASP2, ICH1, NEDD2
Protein NameCASP2
Alternative Name(s)
Caspase-2;CASP-2;;Neural precursor cell expressed developmentally down-regulated protein 2;NEDD-2;Protease ICH-1;Caspase-2 subunit p18;Caspase-2 subunit p13;Caspase-2 subunit p12;
Protein FamilyBelongs to the peptidase C14A family
EntrezGene ID835   (Comparitive Toxicogenomics)
UniProt AC (Human)P42575 (protein sequence)
Enzyme Class3.4.22.55 (BRENDA )
Molecular Weight50685 Dalton
Protein Length452 amino acids (AA)
Genome Browsers NCBI | ENSG00000106144 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG3573 | eggNOG - ENOG410ZQIE
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)