Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name PLPP1 (QuickGO)
Interactive visualization PLPP1 structures
(A quick tutorial to explore the interctive visulaization)

Synonyms PLPP1 , LPP1, PPAP2A
Protein Name PLPP1
Alternative Name(s)
Phospholipid phosphatase 1;;Lipid phosphate phosphohydrolase 1;PAP2-alpha;Phosphatidate phosphohydrolase type 2a;Phosphatidic acid phosphatase 2a;PAP-2a;PAP2a;
EntrezGene ID8611   (Comparitive Toxicogenomics)
UniProt AC (Human) O14494 (protein sequence)
Enzyme ClassEC (BRENDA )
Molecular Weight32156 Dalton
Protein Length284 amino acids (AA)
Genome Browsers NCBI | ENSG00000067113 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree
Classification Superfamily: glucose_lipid phosphatases | Historic class: Phosphatidic acid phosphatase (PAP) | CATH ID: | SCOP Fold: Chloroperoxidase
Phosphatase activityactive | Catalytic signature motif: unknown
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)