Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name BRCA1 (QuickGO)
Interactive visualization of BRCA1 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 6G2I

SynonymsBRCA1, RNF53
Protein NameBRCA1
Alternative Name(s)
Breast cancer type 1 susceptibility protein;;RING finger protein 53;RING-type E3 ubiquitin transferase BRCA1;
Protein FamilynoSimilarity_annotations
EntrezGene ID672   (Comparitive Toxicogenomics)
UniProt AC (Human)P38398 (protein sequence)
Enzyme Class2.3.2.27 (BRENDA )
Molecular Weight207721 Dalton
Protein Length1863 amino acids (AA)
Genome Browsers NCBI | ENSG00000012048 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - ENOG410ITQ4 | eggNOG - ENOG4112BIH
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)