Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name POLR2A (QuickGO)
Interactive visualization of POLR2A structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 3D9N

SynonymsPOLR2A, POLR2
Protein NamePOLR2A
Alternative Name(s)
DNA-directed RNA polymerase II subunit RPB1;RNA polymerase II subunit B1;;DNA-directed RNA polymerase II subunit A;DNA-directed RNA polymerase III largest subunit;RNA-directed RNA polymerase II subunit RPB1;;
Protein FamilyBelongs to the RNA polymerase beta' chain family
EntrezGene ID5430   (Comparitive Toxicogenomics)
UniProt AC (Human)P24928 (protein sequence)
Enzyme Class2.7.7.6 (BRENDA )
Molecular Weight217176 Dalton
Protein Length1970 amino acids (AA)
Genome Browsers NCBI | ENSG00000181222 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG0260 | eggNOG - COG0086
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)