Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last update: 11 Mar, 2019




Gene Name EIF2AK2 (QuickGO)
Interactive visualization of EIF2AK2 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 3UIU

SynonymsEIF2AK2, PKR, PRKR
Protein NameEIF2AK2
Alternative Name(s)
Interferon-induced, double-stranded RNA-activated protein kinase;;Eukaryotic translation initiation factor 2-alpha kinase 2;eIF-2A protein kinase 2;Interferon-inducible RNA-dependent protein kinase;P1/eIF-2A protein kinase;Protein kinase RNA-activated;PKR;Protein kinase R;Tyrosine-protein kinase EIF2AK2;;p68 kinase;
Protein FamilyBelongs to the protein kinase superfamily Ser/Thrprotein kinase family GCN2 subfamily
EntrezGene ID5610   (Comparitive Toxicogenomics)
UniProt AC (Human)P19525 (protein sequence)
Enzyme Class2.7.11.1 (BRENDA )
Molecular Weight62094 Dalton
Protein Length551 amino acids (AA)
Genome Browsers NCBI | ENSG00000055332 (Ensembl) | UCSC | 1000 Genomes
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG1033 | eggNOG - ENOG410XS0B
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)