Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name PTK2 (QuickGO)
Interactive visualization of PTK2 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 4K9Y

SynonymsPTK2, FAK, FAK1
Protein NamePTK2
Alternative Name(s)
Focal adhesion kinase 1;FADK 1;;Focal adhesion kinase-related nonkinase;FRNK;Protein phosphatase 1 regulatory subunit 71;PPP1R71;Protein-tyrosine kinase 2;p125FAK;pp125FAK;
Protein FamilyBelongs to the protein kinase superfamily Tyr proteinkinase family FAK subfamily
EntrezGene ID5747   (Comparitive Toxicogenomics)
UniProt AC (Human)Q05397 (protein sequence)
Enzyme Class2.7.10.2 (BRENDA )
Molecular Weight119233 Dalton
Protein Length1052 amino acids (AA)
Genome Browsers NCBI | ENSG00000169398 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG4257 | eggNOG - ENOG410ZH9Y
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)