Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name ALPL (QuickGO)
Interactive visualization ALPL structures
(A quick tutorial to explore the interctive visulaization)

Synonyms ALPL
Protein Name ALPL
Alternative Name(s)
Alkaline phosphatase, tissue-nonspecific isozyme;AP-TNAP;TNSALP;;Alkaline phosphatase liver/bone/kidney isozyme;
EntrezGene ID249   (Comparitive Toxicogenomics)
UniProt AC (Human) P05186 (protein sequence)
Enzyme ClassEC (BRENDA )
Molecular Weight57305 Dalton
Protein Length524 amino acids (AA)
Genome Browsers NCBI | ENSG00000162551 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree
Classification Superfamily: alkaline phosphatase (AP) | Historic class: Alkaline phosphatase | CATH ID: 3.40.720.10 | SCOP Fold: AP
Phosphatase activityactive | Catalytic signature motif: unknown
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)