Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name TGFBR1 (QuickGO)
Interactive visualization of TGFBR1 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 1PY5

SynonymsTGFBR1, ALK5, SKR4
Protein NameTGFBR1
Alternative Name(s)
TGF-beta receptor type-1;TGFR-1;;Activin A receptor type II-like protein kinase of 53kD;Activin receptor-like kinase 5;ALK-5;ALK5;Serine/threonine-protein kinase receptor R4;SKR4;TGF-beta type I receptor;Transforming growth factor-beta receptor type I;TGF-beta receptor type I;TbetaR-I;
Protein FamilyBelongs to the protein kinase superfamily TKL Ser/Thrprotein kinase family TGFB receptor subfamily
EntrezGene ID7046   (Comparitive Toxicogenomics)
UniProt AC (Human)P36897 (protein sequence)
Enzyme Class2.7.11.30 (BRENDA )
Molecular Weight55960 Dalton
Protein Length503 amino acids (AA)
Genome Browsers NCBI | ENSG00000106799 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG2052 | eggNOG - ENOG410XQT0
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)