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KEGG Pathway - Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human) Name UniProt AC Dephosphorylates following protein substrates: Dephosphorylates following non-protein substrates: DUSP9 Q99956 MAPK3 , MAPK1 , MAPK8 , MAPK9 , MAPK14 , Non-protein substrates of this phosphatase are not reported yet
Name UniProt AC Dephosphorylated by: AXIN1 O15169 PPP1CA , PPP1CB , PPP1CC , PPP2CA , PPP2CB , PPM1A , JAK2 O60674 PTPRC , PTPN1 , PTPN6 , PTPN11 , MYC P01106 PPP2CA , PPP2CB , CTDSP1 , RAF1 P04049 CDC25A , PPP1CA , PPP1CB , PPP1CC , PPP2CA , PPP2CB , PPP5C , PTPN1 , IGF1R P08069 PTPN1 , FGFR2 P21802 DUSP3 , JAK1 P23458 PTPRC , PTPN2 , MAPK3 P27361 CDC25A , DUPD1 , PTPN7 , DUSP5 , DUSP1 , DUSP4 , DUSP9 , DUSP23 , PTPRE , PTPRJ , DUSP3 , PPP2CA , PTPRR , DUSP14 , PIK3R1 P27986 PPM1A , PTPRJ , MAPK1 P28482 CDC25A , DUSP22 , DUPD1 , PTPN7 , DUSP5 , DUSP1 , DUSP4 , DUSP6 , DUSP9 , DUSP7 , DUSP2 , PPP2CA , PPP2CB , PTPRE , PTPRJ , DUSP3 , PTPRR , AKT1 P31749 ACP1 , PHLPP1 , PHLPP2 , PPP2CA , PPP2CB , PPP1CA , PPP1CB , PPP1CC , CTDSP1 , AKT2 P31751 PHLPP1 , PHLPP2 , CTNNB1 P35222 PTPN23 , PTPRF , ACP1 , PTPN14 , PTPN1 , PTPRU , PTPRK , DUSP23 , BMPR1A P36894 CTDNEP1 , IL6ST P40189 PPP2CA , PPP2CB , STAT3 P40763 DUSP22 , PTPN1 , PTPRD , PTPRT , PTPN2 , GSK3B P49841 EPM2A , PPP3CA , PPP3CB , PPP3CC , PTPN1 , JAK3 P52333 PTPRC , PTPN2 , MAPK12 P53778 PTPN3 , SMAD3 P84022 MTMR4 , PPP2CA , PPP2CB , PPM1A , CTDSP1 , CTDSP2 , CTDSPL , MAP2K1 Q02750 PPP2CA , PPP2CB , BMPR2 Q13873 PPP2CA , PPP2CB , SMAD2 Q15796 PPM1A , CTDSP1 , CTDSP2 , CTDSPL , SMAD1 Q15797 PDP1 , PDP2 , PPP2CA , PPP2CB , PPM1A , CTDSP1 , CTDSP2 , CTDSPL , MAPK14 Q16539 DUSP22 , DUPD1 , PTPN7 , DUSP8 , DUSP1 , DUSP9 , DUSP10 , DUSP2 , PPP2CA , PPP2CB , PPM1A , PPM1D , DUSP26 , DUSP3 , DUSP14 , AKT3 Q9Y243 PHLPP1 , PHLPP2 , PPP2CA , PPP2CB , APC P25054 PPP2CB , PPP2CA , REST Q13127 CTDSP1 ,
Non-protein substrates involved in this pathway are unknown (yet!)