Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name PTK2B (QuickGO)
Interactive visualization of PTK2B structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 5TO8

SynonymsPTK2B, FAK2, PYK2, RAFTK
Protein NamePTK2B
Alternative Name(s)
Protein-tyrosine kinase 2-beta;;Calcium-dependent tyrosine kinase;CADTK;Calcium-regulated non-receptor proline-rich tyrosine kinase;Cell adhesion kinase beta;CAK-beta;CAKB;Focal adhesion kinase 2;FADK 2;Proline-rich tyrosine kinase 2;Related adhesion focal tyrosine kinase;RAFTK;
Protein FamilyBelongs to the protein kinase superfamily Tyr proteinkinase family FAK subfamily
EntrezGene ID2185   (Comparitive Toxicogenomics)
UniProt AC (Human)Q14289 (protein sequence)
Enzyme Class2.7.10.2 (BRENDA )
Molecular Weight115875 Dalton
Protein Length1009 amino acids (AA)
Genome Browsers NCBI | ENSG00000120899 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG4257 | eggNOG - ENOG410ZH9Y
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)