Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name PTP4A3 (QuickGO)
Interactive visualization PTP4A3 structures
(A quick tutorial to explore the interctive visulaization)

Synonyms PTP4A3, PRL3
Protein Name PTP4A3
Alternative Name(s)
Protein tyrosine phosphatase type IVA 3;;PRL-R;Protein-tyrosine phosphatase 4a3;Protein-tyrosine phosphatase of regenerating liver 3;PRL-3;
EntrezGene ID11156   (Comparitive Toxicogenomics)
UniProt AC (Human) O75365 (protein sequence)
Enzyme ClassEC (BRENDA )
Molecular Weight19535 Dalton
Protein Length173 amino acids (AA)
Genome Browsers NCBI | ENSG00000184489 (Ensembl) | ENSG00000275575 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree
Classification Superfamily: Class I Cys-based PTPs --> Family: DSP --> Subfamily: PRL | Historic class: Class I Cys-based PTPs --> VH1-like or DSPs --> PRLs | CATH ID: | SCOP Fold: CC1
Phosphatase activityactive | Catalytic signature motif: HCVAGLGR
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)