Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name CHEK2 (QuickGO)
Interactive visualization of CHEK2 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 3VA4

SynonymsCHEK2, CDS1, CHK2, RAD53
Protein NameCHEK2
Alternative Name(s)
Serine/threonine-protein kinase Chk2;;CHK2 checkpoint homolog;Cds1 homolog;Hucds1;hCds1;Checkpoint kinase 2;
Protein FamilyBelongs to the protein kinase superfamily CAMKSer/Thr protein kinase family CHK2 subfamily
EntrezGene ID11200   (Comparitive Toxicogenomics)
UniProt AC (Human)O96017 (protein sequence)
Enzyme Class2.7.11.1 (BRENDA )
Molecular Weight60915 Dalton
Protein Length543 amino acids (AA)
Genome Browsers NCBI | ENSG00000183765 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)