Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name SPHK1 (QuickGO)
Interactive visualization of SPHK1 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 3VZD

SynonymsSPHK1, SPHK, SPK
Protein NameSPHK1
Alternative Name(s)
Sphingosine kinase 1;SK 1;SPK 1;;
Protein FamilynoSimilarity_annotations
EntrezGene ID8877   (Comparitive Toxicogenomics)
UniProt AC (Human)Q9NYA1 (protein sequence)
Enzyme Class2.7.1.91 (BRENDA )
Molecular Weight42518 Dalton
Protein Length384 amino acids (AA)
Genome Browsers NCBI | ENSG00000176170 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG1116 | eggNOG - COG1597
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)