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KEGG Pathway - ErbB signaling pathway - Homo sapiens (human) Phosphatases regulating this pathway are unknown (yet)
Name UniProt AC Dephosphorylated by: ABL1 P00519 PTPN18 , PTPN12 , EGFR P00533 CDC25A , ACP1 , PTPN1 , PTPN9 , PTPRU , PTPRJ , PTPRK , PTPRS , PTPN6 , PTPN11 , PTPN2 , DUSP3 , UBASH3B , PTPRA , PTPRB , PTPN12 , PTPRH , MYC P01106 PPP2CA , PPP2CB , CTDSP1 , RAF1 P04049 CDC25A , PPP1CA , PPP1CB , PPP1CC , PPP2CA , PPP2CB , PPP5C , PTPN1 , ERBB2 P04626 ACPP , PTPN9 , DUSP3 , PTPN6 , PTPN12 , PTPN11 , PTPN18 , PTPN11 , JUN P05412 PPP3CA , PPP3CB , PPP3CC , PRKCB P05771 PHLPP1 , PHLPP2 , PPP1CA , PPP2CA , PPP2CB , SRC P12931 PTPN23 , ACP1 , PPP2CA , PPP2CB , PTPN1 , PTPN21 , PTPN12 , PTPRA , PTPRE , PTPRJ , PTPRH , PTPN6 , PTPN11 , PTPN2 , PRKCA P17252 PHLPP1 , PHLPP2 , PPP1CA , PPP1CB , PPP1CC , PPP2CA , PPP2CB , PLCG1 P19174 PTPN1 , PTPRJ , ELK1 P19419 PPP3CA , PPP3CB , PPP3CC , CBL P22681 PTPRJ , UBASH3B , RPS6KB1 P23443 PPP2CA , PPP2CB , PHLPP1 , PHLPP2 , MAPK3 P27361 CDC25A , DUPD1 , PTPN7 , DUSP5 , DUSP1 , DUSP4 , DUSP9 , DUSP23 , PTPRE , PTPRJ , DUSP3 , PPP2CA , PTPRR , DUSP14 , PIK3R1 P27986 PPM1A , PTPRJ , MAPK1 P28482 CDC25A , DUSP22 , DUPD1 , PTPN7 , DUSP5 , DUSP1 , DUSP4 , DUSP6 , DUSP9 , DUSP7 , DUSP2 , PPP2CA , PPP2CB , PTPRE , PTPRJ , DUSP3 , PTPRR , SHC1 P29353 PTEN , PTPN2 , AKT1 P31749 ACP1 , PHLPP1 , PHLPP2 , PPP2CA , PPP2CB , PPP1CA , PPP1CB , PPP1CC , CTDSP1 , AKT2 P31751 PHLPP1 , PHLPP2 , STAT5A P42229 ACP1 , PTPN1 , PTPN11 , PTPN2 , DUSP3 , MAPK8 P45983 DUSP22 , DUSP8 , DUSP18 , DUSP1 , DUSP9 , DUSP10 , PPP2CA , PPP2CB , DUSP3 , MAPK9 P45984 DUSP19 , DUSP1 , DUSP4 , DUSP9 , DUSP10 , DUSP16 , DUSP3 , DUSP14 , MAP2K4 P45985 PPP2CA , PPP2CB , PPM1A , CRK P46108 PTPN1 , CDKN1B P46527 CDC14A , PPM1H , PPP2CB , PPP2CA , GSK3B P49841 EPM2A , PPP3CA , PPP3CB , PPP3CC , PTPN1 , STAT5B P51692 PTPN1 , PTPN11 , PTPN2 , MAPK10 P53779 DUSP16 , MAP2K1 Q02750 PPP2CA , PPP2CB , PTK2 Q05397 PTPN23 , ACP1 , PPP1CA , PPP1CB , PPP1CC , PTEN , PTPN1 , PTPN12 , UBASH3B , PAK1 Q13153 PPM1F , PPM1E , PPP2CA , PPP2CB , PPM1A , PAK2 Q13177 PPM1A , GAB1 Q13480 PTPN1 , PTPN11 , CAMK2B Q13554 PPP2CA , PPP2CB , CAMK2G Q13555 PPP1CA , PPP1CB , PPP1CC , PPP2CA , PPP2CB , CTDSPL , ERBB4 Q15303 ACP4 , PTPN6 , PTPN11 , BAD Q92934 ALPL , PPP1CA , PPP1CB , PPP1CC , PPP2CA , PPP2CB , PPP3CA , PPP3CB , PPP3CC , PPM1B , PPP5C , CAMK2A Q9UQM7 PPM1F , PPP1CA , PPP1CB , PPP1CC , PPP2CA , PPP2CB , AKT3 Q9Y243 PHLPP1 , PHLPP2 , PPP2CA , PPP2CB ,
ChEBI ID KEGG ID ChEBIasciiName Molecule Dephosphorylated by: CHEBI:16595 C01245 1D-myo-inositol 1,4,5-trisphosphate INPP5B , INPP5A , INPP5E , INPP5J , INPP5K , OCRL , SYNJ1 , SYNJ2 , CHEBI:16618 C05981 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate TNS2 , FIG4 , INPP5B , INPP5E , INPP5K , OCRL , PTEN , PTPRQ , INPP5F , INPP5D , INPPL1 , SYNJ1 , SYNJ2 , TPTE2 ,