Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name PLCG1 (QuickGO)
Interactive visualization of PLCG1 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 2HSP

SynonymsPLCG1, PLC1
Protein NamePLCG1
Alternative Name(s)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1;;PLC-148;Phosphoinositide phospholipase C-gamma-1;Phospholipase C-II;PLC-II;Phospholipase C-gamma-1;PLC-gamma-1;
Protein FamilynoSimilarity_annotations
EntrezGene ID5335   (Comparitive Toxicogenomics)
UniProt AC (Human)P19174 (protein sequence)
Enzyme Class3.1.4.11 (BRENDA )
Molecular Weight148532 Dalton
Protein Length1290 amino acids (AA)
Genome Browsers NCBI | ENSG00000124181 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG1264 | eggNOG - ENOG410XPXE
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)