Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
--------------------------------
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
--------------------------------
299 KEGG pathways;
876 Reactome pathways;
--------------------------------
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023
194 phosphatases have substrate data;
--------------------------------
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
--------------------------------
299 KEGG pathways;
876 Reactome pathways;
--------------------------------
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023
Top
KEGG Pathway - Amphetamine addiction - Homo sapiens (human) 
 | Phosphatases regulating this pathway |
| Protein substrates in this pathway |
| Name | UniProt AC | Dephosphorylated by: |
| JUN | P05412 | PPP3CA, PPP3CB, PPP3CC, |
| PRKCB | P05771 | PHLPP1, PHLPP2, PPP1CA, PPP2CA, PPP2CB, |
| CREB1 | P16220 | PPP2CA, PPP2CB, PTEN, |
| PRKCA | P17252 | PHLPP1, PHLPP2, PPP1CA, PPP1CB, PPP1CC, PPP2CA, PPP2CB, |
| PRKACA | P17612 | PPP2CA, PPP2CB, |
| PPP1CA | P62136 | PPP1CA, |
| CAMK2B | Q13554 | PPP2CA, PPP2CB, |
| CAMK2G | Q13555 | PPP1CA, PPP1CB, PPP1CC, PPP2CA, PPP2CB, CTDSPL, |
| CAMK4 | Q16566 | PPM1F, PPM1E, PPP2CA, PPP2CB, |
| PPP1R1B | Q9UD71 | PPP2CA, PPP2CB, PPP3CA, PPP3CB, PPP3CC, |
| CAMK2A | Q9UQM7 | PPM1F, PPP1CA, PPP1CB, PPP1CC, PPP2CA, PPP2CB, |
| SLC6A3 | Q01959 | PPP2CA, PPP1CA, |
| Non-protein substrates in this pathway |
Non-protein substrates involved in this pathway are unknown (yet!)