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Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
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336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
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299 KEGG pathways;
876 Reactome pathways;
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last update: 11 Mar, 2019

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DEPOD - Phosphatase Search Result

Search results for Historic class - PTPs

Download FASTA sequences in txt format

Entry nameUniProt ACHistoric ClassSCOP FoldEC numberCATH IDSuperfamilyFamilyActivity status
ACP1P24666Class II Cys-based PTPs -> LMWPTPCC23.1.3.2, 3.1.3.483.40.50.2300Class II Cys-based PTPsLMWPTPactive
CDC14AQ9UNH5Class I Cys-based PTPs --> VH1-like or DSPs --> CDC14sCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
CDC14BO60729Class I Cys-based PTPs --> VH1-like or DSPs --> CDC14sCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
CDC14CA4D256Class I Cys-based PTPs --> VH1-like or DSPs --> CDC14sCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
CDC25AP30304Class III Cys-based PTPs --> CDC25sCC33.1.3.483.40.250.10Class III Cys-based PTPsCDC25active
CDC25BP30305Class III Cys-based PTPs --> CDC25sCC33.1.3.483.40.250.10Class III Cys-based PTPsCDC25active
CDC25CP30307Class III Cys-based PTPs --> CDC25sCC33.1.3.483.40.250.10Class III Cys-based PTPsCDC25active
CDKN3Q16667Class I Cys-based PTPs --> VH1-like or DSPs --> CDC14sCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DNAJC6O75061Class I Cys-based PTPs --> VH1-like or DSPs --> PTENsCC13.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUPD1Q68J44Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP1P28562Class I Cys-based PTPs --> VH1-like or DSPs --> MKPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP10Q9Y6W6Class I Cys-based PTPs --> VH1-like or DSPs --> MKPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP11O75319Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.-3.90.190.10Class I Cys-based PTPsDSPactive
DUSP12Q9UNI6Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP13Q6B8I1Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP13Q9UII6Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP14O95147Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP15Q9H1R2Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP16Q9BY84Class I Cys-based PTPs --> VH1-like or DSPs --> MKPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP18Q8NEJ0Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP19Q8WTR2Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP2Q05923Class I Cys-based PTPs --> VH1-like or DSPs --> MKPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP21Q9H596Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP22Q9NRW4Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP23Q9BVJ7Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP26Q9BV47Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP27Q5VZP5Class I Cys-based PTPsCC1NA3.90.190.10Class I Cys-based PTPsDSPactive
DUSP28Q4G0W2Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP3P51452Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP4Q13115Class I Cys-based PTPs --> VH1-like or DSPs --> MKPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP5Q16690Class I Cys-based PTPs --> VH1-like or DSPs --> MKPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP6Q16828Class I Cys-based PTPs --> VH1-like or DSPs --> MKPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP7Q16829Class I Cys-based PTPs --> VH1-like or DSPs --> MKPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP8Q13202Class I Cys-based PTPs --> VH1-like or DSPs --> MKPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
DUSP9Q99956Class I Cys-based PTPs --> VH1-like or DSPs --> MKPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
EPM2AO95278Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
EYA1Q99502Asp-based PTPs --> EYAsHAD3.1.3.483.40.50.12350HADEYAactive
EYA2O00167Asp-based PTPs --> EYAsHAD3.1.3.483.40.50.12350HADEYAactive
EYA3Q99504Asp-based PTPs --> EYAsHAD3.1.3.483.40.50.12350HADEYAactive
EYA4O95677Asp-based PTPs --> EYAsHAD3.1.3.483.40.50.12350HADEYAactive
FAN1Q9Y2M0Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsNANANANANAinactive
GAKO14976Class I Cys-based PTPsCC1NANAClass I Cys-based PTPsDSPactive
MTM1Q13496Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsCC13.1.3.643.90.190.10Class I Cys-based PTPsDSPactive
MTMR1Q13613Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsCC13.1.3.-3.90.190.10Class I Cys-based PTPsDSPactive
MTMR10Q9NXD2Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsCC1NANAClass I Cys-based PTPsDSPinactive
MTMR11A4FU01Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsCC1NANAClass I Cys-based PTPsDSPinactive
MTMR12Q9C0I1Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsCC1NANAClass I Cys-based PTPsDSPinactive
MTMR14Q8NCE2Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsCC13.1.3.-3.90.190.10Class I Cys-based PTPsDSPactive
MTMR2Q13614Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsCC13.1.3.-3.90.190.10Class I Cys-based PTPsDSPactive
MTMR3Q13615Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsCC13.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
MTMR4Q9NYA4Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsCC13.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
MTMR6Q9Y217Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsCC13.1.3.-3.90.190.10Class I Cys-based PTPsDSPactive
MTMR7Q9Y216Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsCC13.1.3.-3.90.190.10Class I Cys-based PTPsDSPactive
MTMR8Q96EF0Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsCC13.1.3.-3.90.190.10Class I Cys-based PTPsDSPactive
MTMR9Q96QG7Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsCC1NANAClass I Cys-based PTPsDSPinactive
PALD1Q9ULE6Class I Cys-based PTPsCC1NA3.90.190.10PTPNAactive
PTENP60484Class I Cys-based PTPs --> VH1-like or DSPs --> PTENsCC13.1.3.16, 3.1.3.48, 3.1.3.673.90.190.10Class I Cys-based PTPsDSPactive
PTP4A1Q93096Class I Cys-based PTPs --> VH1-like or DSPs --> PRLsCC13.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
PTP4A2Q12974Class I Cys-based PTPs --> VH1-like or DSPs --> PRLsCC13.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
PTP4A3O75365Class I Cys-based PTPs --> VH1-like or DSPs --> PRLsCC13.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
PTPDC1A2A3K4Class I Cys-based PTPs --> VH1-like or DSPs --> CDC14sCC13.1.3.-3.90.190.10Class I Cys-based PTPsDSPactive
PTPMT1Q8WUK0Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
PTPN1P18031Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN11Q06124Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN12Q05209Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN13Q12923Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN14Q15678Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN18Q99952Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN2P17706Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN20Q4JDL3Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)NA3.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN21Q16825Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN22Q9Y2R2Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN23Q9H3S7Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN3P26045Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN4P29074Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN5P54829Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN6P29350Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN7P35236Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPN9P43378Class I Cys-based PTPs --> Classical PTPs --> Non-receptor type PTPs (NR-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsNR-PTPactive
PTPRAP18433Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRBP23467Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRCP08575Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRDP23468Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPREP23469Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRFP10586Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRGP23470Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRHQ9HD43Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRJQ12913Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRKQ15262Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRMP28827Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRNQ16849Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC1NA3.90.190.10Class I Cys-based PTPsR-PTPinactive
PTPRN2Q92932Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPROQ16827Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRQQ9UMZ3Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.-, 3.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRRQ15256Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRSQ13332Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRTO14522Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRUQ92729Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
PTPRZ1P23471Class I Cys-based PTPs --> Classical PTPs --> Receptor-type PTPs (R-PTPs)CC13.1.3.483.90.190.10Class I Cys-based PTPsR-PTPactive
RNGTTO60942Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC13.1.3.33, 2.7.7.503.90.190.10Class I Cys-based PTPsDSPactive
SBF1O95248Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsCC1NANAClass I Cys-based PTPsDSPinactive
SBF2Q86WG5Class I Cys-based PTPs --> VH1-like or DSPs --> MyotubularinsCC1NANAClass I Cys-based PTPsDSPinactive
SSH1Q8WYL5Class I Cys-based PTPs --> VH1-like or DSPs --> SlingshotsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
SSH2Q76I76Class I Cys-based PTPs --> VH1-like or DSPs --> SlingshotsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
SSH3Q8TE77Class I Cys-based PTPs --> VH1-like or DSPs --> SlingshotsCC13.1.3.16, 3.1.3.483.90.190.10Class I Cys-based PTPsDSPactive
STYXQ8WUJ0Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC1NA3.90.190.10Class I Cys-based PTPsDSPinactive
STYXL1Q9Y6J8Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPsCC1NA3.90.190.10Class I Cys-based PTPsDSPinactive
TNS1Q9HBL0Class I Cys-based PTPs --> VH1-like or DSPs --> PTENsCC1NA3.90.190.10Class I Cys-based PTPsDSPinactive
TNS2Q63HR2Class I Cys-based PTPs --> VH1-like or DSPs --> PTENsCC13.1.3.-3.90.190.10Class I Cys-based PTPsDSPactive
TNS3Q68CZ2Class I Cys-based PTPsCC1NA3.90.190.10Class I Cys-based PTPsDSPactive
TPTEP56180Class I Cys-based PTPs --> VH1-like or DSPs --> PTENsCC13.1.3.673.90.190.10Class I Cys-based PTPsDSPactive
TPTE2Q6XPS3Class I Cys-based PTPs --> VH1-like or DSPs --> PTENsCC13.1.3.673.90.190.10Class I Cys-based PTPsDSPactive

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