Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name CDC25B (QuickGO)
Interactive visualization CDC25B structures
(A quick tutorial to explore the interctive visulaization)

Synonyms CDC25B, CDC25HU2
Protein Name CDC25B
Alternative Name(s)
M-phase inducer phosphatase 2;;Dual specificity phosphatase Cdc25B;
EntrezGene ID994   (Comparitive Toxicogenomics)
UniProt AC (Human) P30305 (protein sequence)
Enzyme ClassEC (BRENDA )
Molecular Weight64987 Dalton
Protein Length580 amino acids (AA)
Genome Browsers NCBI | ENSG00000101224 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree
Classification Superfamily: Class III Cys-based PTPs --> Family: CDC25 | Historic class: Class III Cys-based PTPs --> CDC25s | CATH ID: | SCOP Fold: CC3
Phosphatase activityactive | Catalytic signature motif: HCEFSSER
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)