Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name PTP4A1 (QuickGO)
Interactive visualization PTP4A1 structures
(A quick tutorial to explore the interctive visulaization)

Synonyms PTP4A1, PRL1, PTPCAAX1
Protein Name PTP4A1
Alternative Name(s)
Protein tyrosine phosphatase type IVA 1;;PTP(CAAXI);Protein-tyrosine phosphatase 4a1;Protein-tyrosine phosphatase of regenerating liver 1;PRL-1;
EntrezGene ID7803   (Comparitive Toxicogenomics)
UniProt AC (Human) Q93096 (protein sequence)
Enzyme ClassEC (BRENDA )
Molecular Weight19815 Dalton
Protein Length173 amino acids (AA)
Genome Browsers NCBI | ENSG00000112245 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree
Classification Superfamily: Class I Cys-based PTPs --> Family: DSP --> Subfamily: PRL | Historic class: Class I Cys-based PTPs --> VH1-like or DSPs --> PRLs | CATH ID: | SCOP Fold: CC1
Phosphatase activityactive | Catalytic signature motif: HCVAGLGR
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)