Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
--------------------------------
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
--------------------------------
299 KEGG pathways;
876 Reactome pathways;
--------------------------------
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023
194 phosphatases have substrate data;
--------------------------------
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
--------------------------------
299 KEGG pathways;
876 Reactome pathways;
--------------------------------
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023
DEPOD - Phosphatase Search Result
Search results for EC number - 3.1.3.16
Download FASTA sequences in txt format
| Entry name | UniProt AC | Historic Class | SCOP Fold | EC number | CATH ID | Superfamily | Family | Activity status |
| CDC14A | Q9UNH5 | Class I Cys-based PTPs --> VH1-like or DSPs --> CDC14s | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| CDC14B | O60729 | Class I Cys-based PTPs --> VH1-like or DSPs --> CDC14s | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| CDC14C | A4D256 | Class I Cys-based PTPs --> VH1-like or DSPs --> CDC14s | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| CDKN3 | Q16667 | Class I Cys-based PTPs --> VH1-like or DSPs --> CDC14s | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| CPPED1 | Q9BRF8 | PSTPs --> PPP | NA | 3.1.3.16 | NA | PPPL | NA | active |
| CTDNEP1 | O95476 | PSTPs --> FCP/SCP | HAD | 3.1.3.16 | 3.40.50.1000 | HAD | FCP | active |
| CTDP1 | Q9Y5B0 | PSTPs --> FCP/SCP | HAD | 3.1.3.16 | 3.40.50.1000 | HAD | FCP | active |
| CTDSP1 | Q9GZU7 | PSTPs --> FCP/SCP | HAD | 3.1.3.16 | 3.40.50.1000 | HAD | FCP | active |
| CTDSP2 | O14595 | PSTPs --> FCP/SCP | HAD | 3.1.3.16 | 3.40.50.1000 | HAD | FCP | active |
| CTDSPL | O15194 | PSTPs --> FCP/SCP | HAD | 3.1.3.16 | 3.40.50.1000 | HAD | FCP | active |
| DUPD1 | Q68J44 | Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP1 | P28562 | Class I Cys-based PTPs --> VH1-like or DSPs --> MKPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP10 | Q9Y6W6 | Class I Cys-based PTPs --> VH1-like or DSPs --> MKPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP12 | Q9UNI6 | Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP13 | Q9UII6 | Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP14 | O95147 | Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP15 | Q9H1R2 | Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP16 | Q9BY84 | Class I Cys-based PTPs --> VH1-like or DSPs --> MKPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP18 | Q8NEJ0 | Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP19 | Q8WTR2 | Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP2 | Q05923 | Class I Cys-based PTPs --> VH1-like or DSPs --> MKPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP21 | Q9H596 | Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP22 | Q9NRW4 | Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP23 | Q9BVJ7 | Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP26 | Q9BV47 | Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP28 | Q4G0W2 | Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP3 | P51452 | Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP4 | Q13115 | Class I Cys-based PTPs --> VH1-like or DSPs --> MKPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP5 | Q16690 | Class I Cys-based PTPs --> VH1-like or DSPs --> MKPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP6 | Q16828 | Class I Cys-based PTPs --> VH1-like or DSPs --> MKPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP7 | Q16829 | Class I Cys-based PTPs --> VH1-like or DSPs --> MKPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP8 | Q13202 | Class I Cys-based PTPs --> VH1-like or DSPs --> MKPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| DUSP9 | Q99956 | Class I Cys-based PTPs --> VH1-like or DSPs --> MKPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| EPM2A | O95278 | Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| ILKAP | Q9H0C8 | PSTPs --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PGAM5 | Q96HS1 | Phosphoglycerate mutase | HP | 3.1.3.16 | 3.40.50.1240 | histidine phosphatase (HP) | PGAM | active |
| PHLPP1 | O60346 | PSTPs --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PHLPP2 | Q6ZVD8 | PSTPs --> PPM --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PPEF1 | O14829 | PSTPs --> PPP --> PP7 | PPPL | 3.1.3.16 | 3.60.21.10 | PPPL | PPP | active |
| PPEF2 | O14830 | PSTPs --> PPP --> PP7 | PPPL | 3.1.3.16 | 3.60.21.10 | PPPL | PPP | active |
| PPM1A | P35813 | PSTPs --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PPM1B | O75688 | PSTPs --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PPM1D | O15297 | PSTPs --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PPM1E | Q8WY54 | PSTPs --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PPM1F | P49593 | PSTPs --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PPM1G | O15355 | PSTPs --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PPM1H | Q9ULR3 | PSTPs --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PPM1J | Q5JR12 | PSTPs --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PPM1K | Q8N3J5 | PSTPs --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PPM1L | Q5SGD2 | PSTPs --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PPM1M | Q96MI6 | PSTPs --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PPM1N | Q8N819 | PSTPs --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PPP1CA | P62136 | PSTPs --> PPP --> PP1 | PPPL | 3.1.3.16 | 3.60.21.10 | PPPL | PPP | active |
| PPP1CB | P62140 | PSTPs --> PPP --> PP1 | PPPL | 3.1.3.16, 3.1.3.53 | 3.60.21.10 | PPPL | PPP | active |
| PPP1CC | P36873 | PSTPs --> PPP --> PP1 | PPPL | 3.1.3.16 | 3.60.21.10 | PPPL | PPP | active |
| PPP2CA | P67775 | PSTPs --> PPP --> PP2A | PPPL | 3.1.3.16 | 3.60.21.10 | PPPL | PPP | active |
| PPP2CB | P62714 | PSTPs --> PPP --> PP2A | PPPL | 3.1.3.16 | 3.60.21.10 | PPPL | PPP | active |
| PPP3CA | Q08209 | PSTPs --> PPP --> PP2B | PPPL | 3.1.3.16 | 3.60.21.10 | PPPL | PPP | active |
| PPP3CB | P16298 | PSTPs --> PPP --> PP2B | PPPL | 3.1.3.16 | 3.60.21.10 | PPPL | PPP | active |
| PPP3CC | P48454 | PSTPs --> PPP --> PP2B | PPPL | 3.1.3.16 | 3.60.21.10 | PPPL | PPP | active |
| PPP4C | P60510 | PSTPs --> PPP --> PP4 | PPPL | 3.1.3.16 | 3.60.21.10 | PPPL | PPP | active |
| PPP5C | P53041 | PSTPs --> PPP --> PP5 | PPPL | 3.1.3.16 | 3.60.21.10 | PPPL | PPP | active |
| PPP6C | O00743 | PSTPs --> PPP --> PP6 | PPPL | 3.1.3.16 | 3.60.21.10 | PPPL | PPP | active |
| PPTC7 | Q8NI37 | PSTPs --> PP2C | PPM | 3.1.3.16 | 3.60.40.10 | PPM | NA | active |
| PTEN | P60484 | Class I Cys-based PTPs --> VH1-like or DSPs --> PTENs | CC1 | 3.1.3.16, 3.1.3.48, 3.1.3.67 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| PTPMT1 | Q8WUK0 | Class I Cys-based PTPs --> VH1-like or DSPs --> Atypical DSPs | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| RPAP2 | Q8IXW5 | RNA polymerase II-associated protein 2 (RPAP2) | RTR1 | 3.1.3.16 | 1.25.40.820 | RPAP | NA | active |
| SSH1 | Q8WYL5 | Class I Cys-based PTPs --> VH1-like or DSPs --> Slingshots | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| SSH2 | Q76I76 | Class I Cys-based PTPs --> VH1-like or DSPs --> Slingshots | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| SSH3 | Q8TE77 | Class I Cys-based PTPs --> VH1-like or DSPs --> Slingshots | CC1 | 3.1.3.16, 3.1.3.48 | 3.90.190.10 | Class I Cys-based PTPs | DSP | active |
| SSU72 | Q9NP77 | SSU72 phosphatase | CC2 | 3.1.3.16 | 3.40.50.2300 | SSU72 | NA | active |
| UBLCP1 | Q8WVY7 | PSTPs --> FCP/SCP | HAD | 3.1.3.16 | 3.40.50.1000 | HAD | FCP | active |