Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
--------------------------------
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
--------------------------------
299 KEGG pathways;
876 Reactome pathways;
--------------------------------
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023
194 phosphatases have substrate data;
--------------------------------
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
--------------------------------
299 KEGG pathways;
876 Reactome pathways;
--------------------------------
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023
Top
KEGG Pathway - Pyrimidine metabolism - Homo sapiens (human) 
 | Phosphatases regulating this pathway |
| Protein substrates in this pathway |
| Name | UniProt AC | Dephosphorylated by: |
| POLR2A | P24928 | CTDSPL2, EYA1, EYA3, CTDP1, RPAP2, CTDSP1, CTDSP2, SSU72, UBLCP1, PPP1CC, PPP1CA, PPP1CB, |
| CAD | P27708 | PPP1CA, PPP1CB, PPP1CC, PPP2CA, PPP2CB, |
| POLD3 | Q15054 | PPP1CA, PPP1CB, PPP1CC, |
| Non-protein substrates in this pathway |
| ChEBI ID | KEGG ID | ChEBIasciiName | Molecule | Dephosphorylated by: |
| CHEBI:17361 | C00055 | cytidine 5'-monophosphate |  | NT5C1A, NT5C3A, |
| CHEBI:16695 | C00105 | uridine 5'-monophosphate |  | NT5C1A, NT5C2, NT5C3A, NT5C, NT5M, |
| CHEBI:15918 | C00239 | 2'-deoxycytosine 5'-monophosphate |  | NT5C1A, NT5C3A, |
| CHEBI:17013 | C00364 | dTMP |  | NT5C2, NT5C3A, NT5C, NT5M, |
| CHEBI:17622 | C00365 | dUMP |  | NT5C1A, NT5C2, NT5C3A, NT5C, NT5M, |
| CHEBI:18116 | C01168 | pseudouridine 5'-phosphate |  | PUDP, |
| CHEBI:28895 | C01368 | 3'-UMP |  | NT5C, NT5M, |