Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
--------------------------------
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
--------------------------------
299 KEGG pathways;
876 Reactome pathways;
--------------------------------
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023
194 phosphatases have substrate data;
--------------------------------
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
--------------------------------
299 KEGG pathways;
876 Reactome pathways;
--------------------------------
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023
Top
KEGG Pathway - Glycolysis / Gluconeogenesis - Homo sapiens (human) 
 | Phosphatases regulating this pathway |
| Name | UniProt AC | Dephosphorylates following protein substrates: | Dephosphorylates following non-protein substrates: |
| FBP2 | O00757 | Protein substrates of this phosphatase are not reported yet | keto-D-fructose 1,6-bisphosphate, D-fructofuranose 1,6-bisphosphate, |
| BPGM | P07738 | Protein substrates of this phosphatase are not reported yet | 2,3-bisphospho-D-glyceric acid, |
| FBP1 | P09467 | Protein substrates of this phosphatase are not reported yet | keto-D-fructose 1,6-bisphosphate, D-fructofuranose 1,6-bisphosphate, |
| PGAM2 | P15259 | Protein substrates of this phosphatase are not reported yet | 2,3-bisphospho-D-glyceric acid, |
| PGAM1 | P18669 | Protein substrates of this phosphatase are not reported yet | 2,3-bisphospho-D-glyceric acid, |
| G6PC | P35575 | Protein substrates of this phosphatase are not reported yet | alpha-D-glucose 6-phosphate, beta-D-glucose 6-phosphate, |
| PGAM4 | Q8N0Y7 | Protein substrates of this phosphatase are not reported yet | 2,3-bisphospho-D-glyceric acid, |
| G6PC3 | Q9BUM1 | Protein substrates of this phosphatase are not reported yet | alpha-D-glucose 6-phosphate, beta-D-glucose 6-phosphate, |
| G6PC2 | Q9NQR9 | Protein substrates of this phosphatase are not reported yet | alpha-D-glucose 6-phosphate, beta-D-glucose 6-phosphate, |
| MINPP1 | Q9UNW1 | Protein substrates of this phosphatase are not reported yet | 1D-myo-inositol 1,3,4,5-tetrakisphosphate, myo-inositol hexakisphosphate, 2,3-bisphospho-D-glyceric acid, |
| Protein substrates in this pathway |
| Non-protein substrates in this pathway |
| ChEBI ID | KEGG ID | ChEBIasciiName | Molecule | Dephosphorylated by: |
| CHEBI:29042 | C00103 | alpha-D-glucose 1-phosphate |  | IMPA1, IMPA2, |
| CHEBI:17665 | C00668 | alpha-D-glucose 6-phosphate |  | G6PC, G6PC2, G6PC3, IMPA1, |
| CHEBI:17720 | C01159 | 2,3-bisphospho-D-glyceric acid |  | BPGM, MINPP1, PGAM4, PGAM1, PGAM2, |
| CHEBI:17719 | C01172 | beta-D-glucose 6-phosphate |  | G6PC, G6PC2, G6PC3, IMPA1, |