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Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
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336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
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299 KEGG pathways;
876 Reactome pathways;
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last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023

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CHEBI:17720

Name 2,3-bisphospho-D-glyceric acidC01159
Download: mol | sdf
Synonyms0(2r)-2,3-bis(phosphonatooxy)propanoate;
2,3-bisphospho-d-glycerate;
2,3-bisphospho-d-glyceric acid;
2,3-bpg;
2,3-disphospho-d-glycerate;
D-greenwald ester;
Dpg;
Definition The D-enantiomer of 2,3-bisphosphoglyceric acid.
Molecular Weight
(Exact mass)
266.0371 (265.9593)
Molecular Formula C3H8O10P2
SMILES OC(=O)[C@@H](COP(O)(O)=O)OP(O)(O)=O
InChI InChI=1S/C3H8O10P2/c4-3(5)2(13-15(9,10)11)1-12-14(6,7)8/h2H,1H2,(H,4,5)(H2,6,7,8)(H2,9,10,11)/t2-/m1/s1
InChI Key XOHUEYCVLUUEJJ-UWTATZPHSA-N
Crosslinking annotations KEGG:C01159 | 3DMET:B01397 | ChEBI:17720 | NIKKAJI:J2.731.659J | PDB-CCD:DG2 | PubChem:4387 |

Pathway ID Pathway Name Pathway Description (KEGG)
map00010Glycolysis / GluconeogenesisGlycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate [MD:M00001]. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate [MD:M00307]. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module [MD:M00002], which is found in almost all organisms and which sometimes contains operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths [MD:M00003].
map01100Metabolic pathwaysNA