Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
--------------------------------
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
--------------------------------
299 KEGG pathways;
876 Reactome pathways;
--------------------------------
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023
194 phosphatases have substrate data;
--------------------------------
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
--------------------------------
299 KEGG pathways;
876 Reactome pathways;
--------------------------------
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023
Top
KEGG Pathway - Carbon metabolism - Homo sapiens (human) 
 | Phosphatases regulating this pathway |
| Name | UniProt AC | Dephosphorylates following protein substrates: | Dephosphorylates following non-protein substrates: |
| PGP | A6NDG6 | Protein substrates of this phosphatase are not reported yet | sn-glycerol 3-phosphate, 2-phosphoglycolic acid, |
| FBP2 | O00757 | Protein substrates of this phosphatase are not reported yet | keto-D-fructose 1,6-bisphosphate, D-fructofuranose 1,6-bisphosphate, |
| FBP1 | P09467 | Protein substrates of this phosphatase are not reported yet | keto-D-fructose 1,6-bisphosphate, D-fructofuranose 1,6-bisphosphate, |
| PGAM2 | P15259 | Protein substrates of this phosphatase are not reported yet | 2,3-bisphospho-D-glyceric acid, |
| PGAM1 | P18669 | Protein substrates of this phosphatase are not reported yet | 2,3-bisphospho-D-glyceric acid, |
| PSPH | P78330 | Protein substrates of this phosphatase are not reported yet | O-phospho-L-serine, |
| PGAM4 | Q8N0Y7 | Protein substrates of this phosphatase are not reported yet | 2,3-bisphospho-D-glyceric acid, |
| Protein substrates in this pathway |
| Non-protein substrates in this pathway |
| ChEBI ID | KEGG ID | ChEBIasciiName | Molecule | Dephosphorylated by: |
| CHEBI:15946 | C00085 | keto-D-fructose 6-phosphate |  | MDP1, |
| CHEBI:61553 | C00085 | D-fructofuranose 6-phosphate | | MDP1, |
| CHEBI:17797 | C00117 | aldehydo-D-ribose 5-phosphate |  | MDP1, |
| CHEBI:52742 | C00117 | D-ribofuranose 5-phosphate | | MDP1, |
| CHEBI:48928 | C00345 | 6-phospho-D-gluconic acid |  | NANP, |
| CHEBI:16905 | C00354 | keto-D-fructose 1,6-bisphosphate |  | FBP1, FBP2, NANP, TIGAR, |
| CHEBI:37736 | C00354 | D-fructofuranose 1,6-bisphosphate | | FBP1, FBP2, NANP, TIGAR, |
| CHEBI:17665 | C00668 | alpha-D-glucose 6-phosphate |  | G6PC, G6PC2, G6PC3, IMPA1, |
| CHEBI:17150 | C00988 | 2-phosphoglycolic acid |  | PGP, |
| CHEBI:15811 | C01005 | O-phospho-L-serine |  | PSPH, |
| CHEBI:17719 | C01172 | beta-D-glucose 6-phosphate |  | G6PC, G6PC2, G6PC3, IMPA1, |