Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name TIGAR (QuickGO)
Interactive visualization TIGAR structures
(A quick tutorial to explore the interctive visulaization)

Synonyms TIGAR , C12orf5
Protein Name TIGAR
Alternative Name(s)
Fructose-2,6-bisphosphatase TIGAR;;TP53-induced glycolysis and apoptosis regulator;TP53-induced glycolysis regulatory phosphatase;
EntrezGene ID57103   (Comparitive Toxicogenomics)
UniProt AC (Human) Q9NQ88 (protein sequence)
Enzyme ClassEC (BRENDA )
Molecular Weight30063 Dalton
Protein Length270 amino acids (AA)
Genome Browsers NCBI | ENSG00000078237 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree
Classification Superfamily: histidine phosphatase (HP) | Historic class: Phosphoglycerate mutase | CATH ID: | SCOP Fold: HP
Phosphatase activityactive | Catalytic signature motif: unknown
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)