Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name MAP4K1 (QuickGO)
Interactive visualization of MAP4K1 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: NA

SynonymsMAP4K1, HPK1
Protein NameMAP4K1
Alternative Name(s)
Mitogen-activated protein kinase kinase kinase kinase 1;;Hematopoietic progenitor kinase;MAPK/ERK kinase kinase kinase 1;MEK kinase kinase 1;MEKKK 1;
Protein FamilyBelongs to the protein kinase superfamily STE Ser/Thrprotein kinase family STE20 subfamily
EntrezGene ID11184   (Comparitive Toxicogenomics)
UniProt AC (Human)Q92918 (protein sequence)
Enzyme Class2.7.11.1 (BRENDA )
Molecular Weight91296 Dalton
Protein Length833 amino acids (AA)
Genome Browsers NCBI | ENSG00000104814 (Ensembl) | ENSG00000282928 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG0576 | eggNOG - ENOG410XP9G
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)