Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name ACLY (QuickGO)
Interactive visualization of ACLY structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 5TE1

Protein NameACLY
Alternative Name(s)
ATP-citrate synthase;;ATP-citrate (pro-S-)-lyase;ACL;Citrate cleavage enzyme;
Protein FamilyIn the N-terminal section belongs to the succinate/malate CoA ligase beta subunit family , In the C-terminal section belongs to the succinate/malate CoA ligase alpha subunit family
EntrezGene ID47   (Comparitive Toxicogenomics)
UniProt AC (Human)P53396 (protein sequence)
Enzyme Class2.3.3.8 (BRENDA )
Molecular Weight120839 Dalton
Protein Length1101 amino acids (AA)
Genome Browsers NCBI | ENSG00000131473 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG1254 | eggNOG - COG0045 | eggNOG - COG0074 | eggNOG - COG0372
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)