DEPOD - human DEPhOsphorylation Database

Basic Information
Phosphatases
Pathway

Name	6-phospho-D-gluconic acid	Download: mol \| sdf
Synonyms	06-o-phosphonato-d-gluconate; 6-phospho-d-gluconate; 6-phosphogluconate; 6-phosphogluconic acid;
Definition	A gluconic acid phosphate having the phosphate group at the 6-position. It is an intermediate in the pentose phosphate pathway.
Molecular Weight (Exact mass)	276.1352 (276.0246)
Molecular Formula	C6H13O10P
SMILES	O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O
InChI	InChI=1S/C6H13O10P/c7-2(1-16-17(13,14)15)3(8)4(9)5(10)6(11)12/h2-5,7-10H,1H2,(H,11,12)(H2,13,14,15)/t2-,3-,4+,5-/m1/s1
InChI Key	BIRSGZKFKXLSJQ-SQOUGZDYSA-N
Crosslinking annotations	KEGG:C00345 \| 3DMET:B01221 \| ChEBI:48928 \| ChEMBL:CHEMBL1230513 \| KNApSAcK:C00007481 \| NIKKAJI:J1.343.743B \| PDB-CCD:6PG \| PubChem:3638 \|

Pathway ID	Pathway Name	Pathway Description (KEGG)
map00030	Pentose phosphate pathway	The pentose phosphate pathway is a process of glucose turnover that produces NADPH as reducing equivalents and pentoses as essential parts of nucleotides. There are two different phases in the pathway. One is irreversible oxidative phase in which glucose-6P is converted to ribulose-5P by oxidative decarboxylation, and NADPH is generated [MD:M00006]. The other is reversible non-oxidative phase in which phosphorylated sugars are interconverted to generate xylulose-5P, ribulose-5P, and ribose-5P [MD:M00007]. Phosphoribosyl pyrophosphate (PRPP) formed from ribose-5P [MD:M00005] is an activated compound used in the biosynthesis of histidine and purine/pyrimidine nucleotides. This pathway map also shows the Entner-Doudoroff pathway where 6-P-gluconate is dehydrated and then cleaved into pyruvate and glyceraldehyde-3P [MD:M00008].
map01100	Metabolic pathways	NA
map01110	Biosynthesis of secondary metabolites	NA
map01120	Microbial metabolism in diverse environments	NA
map01130	Biosynthesis of antibiotics	NA
map01200	Carbon metabolism	Carbon metabolism is the most basic aspect of life. This map presents an overall view of central carbon metabolism, where the number of carbons is shown for each compound denoted by a circle, excluding a cofactor (CoA, CoM, THF, or THMPT) that is replaced by an asterisk. The map contains carbon utilization pathways of glycolysis (map00010), pentose phosphate pathway (map00030), and citrate cycle (map00020), and six known carbon fixation pathways (map00710 and map00720) as well as some pathways of methane metabolism (map00680). The six carbon fixation pathways are: (1) reductive pentose phosphate cycle (Calvin cycle) in plants and cyanobacteria that perform oxygenic photosynthesis, (2) reductive citrate cycle in photosynthetic green sulfur bacteria and some chemolithoautotrophs, (3) 3-hydroxypropionate bi-cycle in photosynthetic green nonsulfur bacteria, two variants of 4-hydroxybutyrate pathways in Crenarchaeota called (4) hydroxypropionate-hydroxybutyrate cycle and (5) dicarboxylate-hydroxybutyrate cycle, and (6) reductive acetyl-CoA pathway in methanogenic bacteria.

CHEBI:48928