Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023




Gene Name SIRT2 (QuickGO)
Interactive visualization of SIRT2 structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 5DY4

SynonymsSIRT2, SIR2L, SIR2L2
Protein NameSIRT2
Alternative Name(s)
NAD-dependent protein deacetylase sirtuin-2;3.5.1.-;Regulatory protein SIR2 homolog 2;SIR2-like protein 2;
Protein FamilyBelongs to the sirtuin family Class I subfamily
EntrezGene ID22933   (Comparitive Toxicogenomics)
UniProt AC (Human)Q8IXJ6 (protein sequence)
Enzyme ClassN/A
Molecular Weight43182 Dalton
Protein Length389 amino acids (AA)
Genome Browsers NCBI | ENSG00000068903 (Ensembl) | ENSG00000283100 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG2682 | eggNOG - COG0846
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)